Entity Details

Primary name CD34_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP28906
EntryNameCD34_HUMAN
FullNameHematopoietic progenitor cell antigen CD34
TaxID9606
Evidenceevidence at protein level
Length385
SequenceStatuscomplete
DateCreated1992-12-01
DateModified2021-06-02

Ontological Relatives

GenesCD34

GO terms

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GOName
GO:0001894 tissue homeostasis
GO:0001935 endothelial cell proliferation
GO:0003094 glomerular filtration
GO:0003158 endothelium development
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007160 cell-matrix adhesion
GO:0007165 signal transduction
GO:0008134 transcription factor binding
GO:0008217 regulation of blood pressure
GO:0009897 external side of plasma membrane
GO:0009925 basal plasma membrane
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0016324 apical plasma membrane
GO:0030097 hemopoiesis
GO:0030195 negative regulation of blood coagulation
GO:0030246 carbohydrate binding
GO:0032703 negative regulation of interleukin-2 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0032733 positive regulation of interleukin-10 production
GO:0035759 mesangial cell-matrix adhesion
GO:0036053 glomerular endothelium fenestra
GO:0038001 paracrine signaling
GO:0042482 positive regulation of odontogenesis
GO:0043199 sulfate binding
GO:0045019 negative regulation of nitric oxide biosynthetic process
GO:0045171 intercellular bridge
GO:0045766 positive regulation of angiogenesis
GO:0048471 perinuclear region of cytoplasm
GO:0048870 cell motility
GO:0050776 regulation of immune response
GO:0050900 leukocyte migration
GO:0060290 transdifferentiation
GO:0061042 vascular wound healing
GO:0071425 hematopoietic stem cell proliferation
GO:0071636 positive regulation of transforming growth factor beta production
GO:0071657 positive regulation of granulocyte colony-stimulating factor production
GO:0071971 extracellular exosome assembly
GO:0072011 glomerular endothelium development
GO:0072089 stem cell proliferation
GO:0072254 metanephric glomerular mesangial cell differentiation
GO:0098609 cell-cell adhesion
GO:1900035 negative regulation of cellular response to heat
GO:1900038 negative regulation of cellular response to hypoxia
GO:1900168 positive regulation of glial cell-derived neurotrophic factor production
GO:1901215 negative regulation of neuron death
GO:2001214 positive regulation of vasculogenesis

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR008083 CD34 antigenFamilyFamily
IPR013836 CD34/PodocalyxinFamilyFamily

Diseases

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Interactions

4 interactions