Entity Details

Primary name GFRP_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP30047
EntryNameGFRP_HUMAN
FullNameGTP cyclohydrolase 1 feedback regulatory protein
TaxID9606
Evidenceevidence at protein level
Length84
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesGCHFR

GO terms

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GOName
GO:0004857 enzyme inhibitor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006809 nitric oxide biosynthetic process
GO:0009890 negative regulation of biosynthetic process
GO:0016597 amino acid binding
GO:0030425 dendrite
GO:0030742 GTP-dependent protein binding
GO:0031965 nuclear membrane
GO:0032991 protein-containing complex
GO:0042133 neurotransmitter metabolic process
GO:0042470 melanosome
GO:0043105 negative regulation of GTP cyclohydrolase I activity
GO:0044549 GTP cyclohydrolase binding
GO:0044877 protein-containing complex binding
GO:0046146 tetrahydrobiopterin metabolic process
GO:0065003 protein-containing complex assembly

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus
Nucleus membrane

Domains

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DomainNameCategoryType
IPR009112 GTP cyclohydrolase I, feedback regulatory proteinFamilyFamily
IPR036717 GFRP superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
GFRP_HUMANGCH1_HUMANBioGRID, HPRD, IntAct16696853 8702680 details
GFRP_HUMANGFRP_HUMANHPRD9092499 details