Entity Details

Primary name COR1A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP31146
EntryNameCOR1A_HUMAN
FullNameCoronin-1A
TaxID9606
Evidenceevidence at protein level
Length461
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesCORO1A

GO terms

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GOName
GO:0001772 immunological synapse
GO:0001845 phagolysosome assembly
GO:0001891 phagocytic cup
GO:0003723 RNA binding
GO:0003779 actin binding
GO:0003785 actin monomer binding
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0005829 cytosol
GO:0005884 actin filament
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0006816 calcium ion transport
GO:0006909 phagocytosis
GO:0007015 actin filament organization
GO:0008022 protein C-terminus binding
GO:0008092 cytoskeletal protein binding
GO:0008360 regulation of cell shape
GO:0016020 membrane
GO:0016477 cell migration
GO:0030027 lamellipodium
GO:0030036 actin cytoskeleton organization
GO:0030335 positive regulation of cell migration
GO:0030424 axon
GO:0030595 leukocyte chemotaxis
GO:0030670 phagocytic vesicle membrane
GO:0030864 cortical actin cytoskeleton
GO:0031339 negative regulation of vesicle fusion
GO:0031589 cell-substrate adhesion
GO:0032036 myosin heavy chain binding
GO:0032796 uropod organization
GO:0032956 regulation of actin cytoskeleton organization
GO:0032991 protein-containing complex
GO:0038180 nerve growth factor signaling pathway
GO:0042102 positive regulation of T cell proliferation
GO:0042803 protein homodimerization activity
GO:0043029 T cell homeostasis
GO:0043320 natural killer cell degranulation
GO:0043524 negative regulation of neuron apoptotic process
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0045087 innate immune response
GO:0045335 phagocytic vesicle
GO:0048873 homeostasis of number of cells within a tissue
GO:0050918 positive chemotaxis
GO:0051015 actin filament binding
GO:0051126 negative regulation of actin nucleation
GO:0051279 regulation of release of sequestered calcium ion into cytosol
GO:0061502 early endosome to recycling endosome transport
GO:0070062 extracellular exosome
GO:0071353 cellular response to interleukin-4
GO:0098978 glutamatergic synapse

Subcellular Location

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Subcellular Location
Cytoplasm
Cytoplasmic vesicle

Domains

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DomainNameCategoryType
IPR001680 WD40 repeatRepeatRepeat
IPR015048 Domain of unknown function DUF1899DomainDomain
IPR015049 Trimerisation motifDomainDomain
IPR015505 CoroninFamilyFamily
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR029508 Coronin 1AFamilyFamily
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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