Entity Details

Primary name FGF9_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP31371
EntryNameFGF9_HUMAN
FullNameFibroblast growth factor 9
TaxID9606
Evidenceevidence at protein level
Length208
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesFGF9

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0001934 positive regulation of protein phosphorylation
GO:0005104 fibroblast growth factor receptor binding
GO:0005576 extracellular region
GO:0005604 basement membrane
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0007165 signal transduction
GO:0007267 cell-cell signaling
GO:0008083 growth factor activity
GO:0008201 heparin binding
GO:0008284 positive regulation of cell population proliferation
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0008584 male gonad development
GO:0009887 animal organ morphogenesis
GO:0010628 positive regulation of gene expression
GO:0021762 substantia nigra development
GO:0030154 cell differentiation
GO:0030324 lung development
GO:0030334 regulation of cell migration
GO:0043410 positive regulation of MAPK cascade
GO:0050679 positive regulation of epithelial cell proliferation
GO:0051781 positive regulation of cell division
GO:0051897 positive regulation of protein kinase B signaling
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation
GO:1904754 positive regulation of vascular associated smooth muscle cell migration
GO:1905931 negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR002209 Fibroblast growth factor familyFamilyFamily
IPR008996 Cytokine IL1/FGFFamilyHomologous superfamily
IPR028251 Fibroblast growth factor 9FamilyFamily

Diseases

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Disease IDSourceNameDescription
612961 OMIMMultiple synostoses syndrome 3 (SYNS3)A bone disease characterized by multiple progressive joint fusions that commonly involve proximal interphalangeal, tarsal-carpal, humeroradial and cervical spine joints. Additional features can include progressive conductive deafness and facial dysmorphism. The disease is caused by variants affecting the gene represented in this entry.

Interactions

5 interactions