Entity Details

Primary name GALNS_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP34059
EntryNameGALNS_HUMAN
FullNameN-acetylgalactosamine-6-sulfatase
TaxID9606
Evidenceevidence at protein level
Length522
SequenceStatuscomplete
DateCreated1994-02-01
DateModified2021-06-02

Ontological Relatives

GenesGALNS

GO terms

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GOName
GO:0003943 N-acetylgalactosamine-4-sulfatase activity
GO:0004065 arylsulfatase activity
GO:0005576 extracellular region
GO:0008484 sulfuric ester hydrolase activity
GO:0035578 azurophil granule lumen
GO:0042340 keratan sulfate catabolic process
GO:0043202 lysosomal lumen
GO:0043312 neutrophil degranulation
GO:0043890 N-acetylgalactosamine-6-sulfatase activity
GO:0046872 metal ion binding
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Lysosome

Domains

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DomainNameCategoryType
IPR000917 Sulfatase, N-terminalDomainDomain
IPR017850 Alkaline-phosphatase-like, core domain superfamilyFamilyHomologous superfamily
IPR024607 Sulfatase, conserved siteSiteConserved site
IPR035626 N-acetylgalactosamine-6-sulfataseFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB09301 Chondroitin sulfateDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
GALNS_HUMANMTR1A_HUMANBioGRID, IntAct26514267 details
GALNS_HUMANNEUR1_HUMANBioGRID8910459 details