Entity Details

Primary name UD13_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP35503
EntryNameUD13_HUMAN
FullNameUDP-glucuronosyltransferase 1A3
TaxID9606
Evidenceevidence at protein level
Length534
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesUGT1A3

GO terms

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GOName
GO:0001972 retinoic acid binding
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0008210 estrogen metabolic process
GO:0015020 glucuronosyltransferase activity
GO:0016021 integral component of membrane
GO:0019899 enzyme binding
GO:0030522 intracellular receptor signaling pathway
GO:0032782 bile acid secretion
GO:0042573 retinoic acid metabolic process
GO:0042803 protein homodimerization activity
GO:0045922 negative regulation of fatty acid metabolic process
GO:0046982 protein heterodimerization activity
GO:0052695 cellular glucuronidation
GO:0052696 flavonoid glucuronidation
GO:0052697 xenobiotic glucuronidation
GO:0070640 vitamin D3 metabolic process
GO:1904224 negative regulation of glucuronosyltransferase activity
GO:2001030 negative regulation of cellular glucuronidation

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR002213 UDP-glucuronosyl/UDP-glucosyltransferaseFamilyFamily
IPR035595 UDP-glycosyltransferase family, conserved siteDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00197 TroglitazoneDrugbanksmall molecule
DB00227 LovastatinDrugbanksmall molecule
DB00295 MorphineDrugbanksmall molecule
DB00313 Valproic acidDrugbanksmall molecule
DB00327 HydromorphoneDrugbanksmall molecule
DB00434 CyproheptadineDrugbanksmall molecule
DB00455 LoratadineDrugbanksmall molecule
DB00503 RitonavirDrugbanksmall molecule
DB00555 LamotrigineDrugbanksmall molecule
DB00586 DiclofenacDrugbanksmall molecule
DB00641 SimvastatinDrugbanksmall molecule
DB00678 LosartanDrugbanksmall molecule
DB00712 FlurbiprofenDrugbanksmall molecule
DB00714 ApomorphineDrugbanksmall molecule
DB00749 EtodolacDrugbanksmall molecule
DB00783 EstradiolDrugbanksmall molecule
DB00788 NaproxenDrugbanksmall molecule
DB00794 PrimidoneDrugbanksmall molecule
DB00796 Candesartan cilexetilDrugbanksmall molecule
DB00966 TelmisartanDrugbanksmall molecule
DB00973 EzetimibeDrugbanksmall molecule
DB00977 EthinylestradiolDrugbanksmall molecule
DB01029 IrbesartanDrugbanksmall molecule
DB01050 IbuprofenDrugbanksmall molecule
DB01076 AtorvastatinDrugbanksmall molecule
DB01095 FluvastatinDrugbanksmall molecule
DB01217 AnastrozoleDrugbanksmall molecule
DB01241 GemfibrozilDrugbanksmall molecule
DB01252 MitiglinideDrugbanksmall molecule
DB01544 FlunitrazepamDrugbanksmall molecule
DB01609 DeferasiroxSwissprotsmall molecule
DB04725 LicofeloneDrugbanksmall molecule
DB04953 EzogabineDrugbanksmall molecule
DB05928 DovitinibDrugbanksmall molecule
DB06210 EltrombopagDrugbanksmall molecule
DB06230 NalmefeneDrugbanksmall molecule
DB06403 AmbrisentanDrugbanksmall molecule
DB06510 MuraglitazarDrugbanksmall molecule
DB06741 GavestinelDrugbanksmall molecule
DB08860 PitavastatinDrugbanksmall molecule
DB08930 DolutegravirDrugbanksmall molecule
DB09038 EmpagliflozinDrugbanksmall molecule
DB09213 DexibuprofenDrugbanksmall molecule
DB11689 SelumetinibDrugbanksmall molecule
DB11691 NaldemedineDrugbanksmall molecule
DB11796 FostemsavirDrugbanksmall molecule
DB11943 DelafloxacinDrugbanksmall molecule
DB12070 LetermovirDrugbanksmall molecule
DB12130 LorlatinibDrugbanksmall molecule
DB13874 EnasidenibDrugbanksmall molecule
DB13919 CandesartanDrugbanksmall molecule
DB13997 Baloxavir marboxilDrugbanksmall molecule
DB14635 Curcumin sulfateDrugbanksmall molecule