Entity Details

Primary name SOX6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP35712
EntryNameSOX6_HUMAN
FullNameTranscription factor SOX-6
TaxID9606
Evidenceevidence at protein level
Length828
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesSOX6

GO terms

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GOName
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001217 DNA-binding transcription repressor activity
GO:0001502 cartilage condensation
GO:0002062 chondrocyte differentiation
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007417 central nervous system development
GO:0007517 muscle organ development
GO:0021529 spinal cord oligodendrocyte cell differentiation
GO:0032332 positive regulation of chondrocyte differentiation
GO:0045165 cell fate commitment
GO:0048708 astrocyte differentiation
GO:0051216 cartilage development
GO:0061036 positive regulation of cartilage development
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:2000726 negative regulation of cardiac muscle cell differentiation
GO:2000741 positive regulation of mesenchymal stem cell differentiation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR009071 High mobility group box domainDomainDomain
IPR027153 Transcription factor SOX-6FamilyFamily
IPR036910 High mobility group box domain superfamilyFamilyHomologous superfamily

Diseases

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