Entity Details

Primary name ODO2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP36957
EntryNameODO2_HUMAN
FullNameDihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length453
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesDLST

GO terms

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GOName
GO:0004149 dihydrolipoyllysine-residue succinyltransferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0006091 generation of precursor metabolites and energy
GO:0006099 tricarboxylic acid cycle
GO:0006103 2-oxoglutarate metabolic process
GO:0006104 succinyl-CoA metabolic process
GO:0006554 lysine catabolic process
GO:0016020 membrane
GO:0016746 acyltransferase activity
GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine
GO:0034451 centriolar satellite
GO:0045252 oxoglutarate dehydrogenase complex
GO:0106077 histone succinylation

Subcellular Location

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Subcellular Location
Mitochondrion matrix
Nucleus

Domains

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DomainNameCategoryType
IPR000089 Biotin/lipoyl attachmentDomainDomain
IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domainDomainDomain
IPR003016 2-oxo acid dehydrogenase, lipoyl-binding siteSiteBinding site
IPR006255 Dihydrolipoamide succinyltransferaseFamilyFamily
IPR011053 Single hybrid motifFamilyHomologous superfamily
IPR023213 Chloramphenicol acetyltransferase-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

86 interactions

InteractorPartnerSourcesPublicationsLink
ODO2_HUMANZHX1_HUMANBioGRID, HPRD, IntAct16169070 details
ODO2_HUMANPAK4_HUMANBioGRID, HPRD, IntAct16169070 details
ODO2_HUMANZBT16_HUMANBioGRID, HPRD, IntAct16169070 details
ODO2_HUMANARI2_HUMANBioGRID, HPRD, IntAct16169070 details
ODO2_HUMANPROF2_HUMANBioGRID, HPRD, IntAct16169070 details
ODO2_HUMANDLG5_HUMANBioGRID, HPRD, IntAct16169070 details
ODO2_HUMANFLII_HUMANBioGRID, HPRD, IntAct16169070 details
ODO2_HUMANNP1L1_HUMANBioGRID, HPRD, IntAct16169070 29128334 details
ODO2_HUMANCCD86_HUMANBioGRID, HPRD, IntAct16169070 details
ODO2_HUMANRUSC2_HUMANBioGRID, HPRD, IntAct16169070 details
ODO2_HUMANSCFD1_HUMANBioGRID, HPRD, IntAct16169070 details
ODO2_HUMANUMPS_HUMANHPRD, IntAct16169070 details
ODO2_HUMANPRS6B_HUMANBioGRID, IntAct29128334 32814053 details
ODO2_HUMANPIAS4_HUMANIntAct32814053 details
ODO2_HUMANTPX2_HUMANIntAct32814053 details
ODO2_HUMANSERC_HUMANIntAct32814053 details
ODO2_HUMANFAH2A_HUMANIntAct32814053 details
ODO2_HUMANM2OM_HUMANIntAct32814053 details
ODO2_HUMANCMTA2_HUMANIntAct32814053 details
ODO2_HUMANTPGS2_HUMANIntAct32814053 details
ODO2_HUMANNKG2A_HUMANIntAct32814053 details
ODO2_HUMANNEK6_HUMANIntAct32814053 details
ODO2_HUMANPOC1A_HUMANIntAct32814053 details
ODO2_HUMANGNAO_HUMANIntAct32814053 details
ODO2_HUMANPSMD2_HUMANIntAct32814053 details
ODO2_HUMANRAB31_HUMANIntAct32814053 details
ODO2_HUMANGCDH_HUMANIntAct28062662 details
ODO2_HUMANMYNN_HUMANIntAct32814053 details
ODO2_HUMANPPE1_HUMANIntAct32814053 details
ODO2_HUMANHUWE1_HUMANIntAct32814053 details
ODO2_HUMANTMX3_HUMANIntAct32814053 details
ODO2_HUMANMBPHL_HUMANIntAct32814053 details
ODO2_HUMANLEG1_HUMANIntAct32814053 details
ODO2_HUMANTSP3_HUMANIntAct32814053 details
ODO2_HUMANPYGO1_HUMANIntAct32814053 details
ODO2_HUMANUBP12_HUMANIntAct32814053 details
ODO2_HUMANIDHC_HUMANIntAct32814053 details
ODO2_HUMANMAGA2_HUMANIntAct32814053 details
ODO2_HUMANRBM5_HUMANIntAct32814053 details
ODO2_HUMANPBIR3_HUMANIntAct32814053 details
ODO2_HUMANDRB3_HUMANIntAct32814053 details
ODO2_HUMANEPCAM_HUMANIntAct32814053 details
ODO2_HUMANRASF2_HUMANIntAct32814053 details
ODO2_HUMANNLRP3_HUMANIntAct32814053 details
ODO2_HUMANARG28_HUMANIntAct32814053 details
ODO2_HUMAN3BHS1_HUMANIntAct32814053 details
ODO2_HUMANT23O_HUMANIntAct32814053 details
ODO2_HUMANSPF45_HUMANIntAct32814053 details
ODO2_HUMANISY1_HUMANIntAct32814053 details
ODO2_HUMANCXA5_HUMANIntAct32814053 details
ODO2_HUMANRAP1B_HUMANIntAct32814053 details
ODO2_HUMANZHX1R_HUMANIntAct32814053 details
ODO2_HUMANMMAB_HUMANIntAct32814053 details
ODO2_HUMANTSAP1_HUMANIntAct32814053 details
ODO2_HUMANCNOT3_HUMANIntAct32814053 details
ODO2_HUMANDRC7_HUMANIntAct32814053 details
ODO2_HUMANTBB5_HUMANIntAct32814053 details
ODO2_HUMANSP6_HUMANIntAct32814053 details
ODO2_HUMANLEG8_HUMANIntAct32814053 details
ODO2_HUMANPRAM_HUMANIntAct32814053 details
ODO2_HUMANSPRE2_HUMANIntAct32814053 details
ODO2_HUMANLEG1H_HUMANIntAct32814053 details
ODO2_HUMANFUT2_HUMANIntAct32814053 details
ODO2_HUMANHD_HUMANIntAct32814053 details
ODO2_HUMANMFI_HUMANIntAct32814053 details
ODO2_HUMANNF2IP_HUMANIntAct32814053 details
ODO2_HUMANDNSL1_HUMANIntAct32814053 details
ODO2_HUMANODO1_HUMANBioGRID, HPRD22939629 26344197 9727038 details
ODO2_HUMANNXPE1_HUMANIntAct32814053 details
ODO2_HUMANTBB4B_HUMANBioGRID, HPRD16169070 details
ODO2_HUMANEVA1B_HUMANIntAct32814053 details
ODO2_HUMANSIAH2_HUMANBioGRID15466852 30771432 details
ODO2_HUMANTNMD_HUMANIntAct32814053 details
ODO2_HUMANMAVS_HUMANIntAct32814053 details
ODO2_HUMANCREL2_HUMANIntAct32814053 details
ODO2_HUMANOGT1_HUMANBioGRID32994395 details
ODO2_HUMANSPT17_HUMANIntAct32814053 details
ODO2_HUMANCA216_HUMANIntAct32814053 details
ODO2_HUMANRAB3C_HUMANIntAct32814053 details
ODO2_HUMANEGFL8_HUMANIntAct32814053 details
ODO2_HUMANTHAP7_HUMANIntAct32814053 details
ODO2_HUMANGCR_HUMANBioGRID28611094 31182584 details
ODO2_HUMANTBB2A_HUMANIntAct16169070 details
ODO2_HUMANCLUS_HUMANIntAct31413325 details
ODO2_HUMANIKKE_HUMANIntAct17353931 details
ODO2_HUMANMFF_HUMANIntAct29128334 details