Entity Details

Primary name IL15_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP40933
EntryNameIL15_HUMAN
FullNameInterleukin-15
TaxID9606
Evidenceevidence at protein level
Length162
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GenesIL15

GO terms

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GOName
GO:0001819 positive regulation of cytokine production
GO:0001866 NK T cell proliferation
GO:0005125 cytokine activity
GO:0005126 cytokine receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007165 signal transduction
GO:0007260 tyrosine phosphorylation of STAT protein
GO:0007267 cell-cell signaling
GO:0007568 aging
GO:0008284 positive regulation of cell population proliferation
GO:0009986 cell surface
GO:0014732 skeletal muscle atrophy
GO:0016607 nuclear speck
GO:0030212 hyaluronan metabolic process
GO:0030225 macrophage differentiation
GO:0032740 positive regulation of interleukin-17 production
GO:0032819 positive regulation of natural killer cell proliferation
GO:0032825 positive regulation of natural killer cell differentiation
GO:0034105 positive regulation of tissue remodeling
GO:0035723 interleukin-15-mediated signaling pathway
GO:0042102 positive regulation of T cell proliferation
GO:0042119 neutrophil activation
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0045062 extrathymic T cell selection
GO:0045580 regulation of T cell differentiation
GO:0048469 cell maturation
GO:0048535 lymph node development
GO:0048662 negative regulation of smooth muscle cell proliferation
GO:0050691 regulation of defense response to virus by host
GO:0050729 positive regulation of inflammatory response
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050766 positive regulation of phagocytosis
GO:0050778 positive regulation of immune response
GO:0071305 cellular response to vitamin D
GO:0120163 negative regulation of cold-induced thermogenesis
GO:1904100 positive regulation of protein O-linked glycosylation

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus
Secreted

Domains

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DomainNameCategoryType
IPR003443 Interleukin-15/Interleukin-21 familyFamilyFamily
IPR009079 Four-helical cytokine-like, coreFamilyHomologous superfamily
IPR020439 Interleukin-15FamilyFamily
IPR020466 Interleukin-15, mammalFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB01327 CefazolinDrugbanksmall molecule