Entity Details

Primary name NKX26_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionA6NCS4
EntryNameNKX26_HUMAN
FullNameHomeobox protein Nkx-2.6
TaxID9606
Evidenceevidence at protein level
Length301
SequenceStatuscomplete
DateCreated2007-09-11
DateModified2021-06-02

Ontological Relatives

GenesNKX2-6

GO terms

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GOName
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008284 positive regulation of cell population proliferation
GO:0021854 hypothalamus development
GO:0030154 cell differentiation
GO:0035050 embryonic heart tube development
GO:0043066 negative regulation of apoptotic process
GO:0043586 tongue development
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048565 digestive tract development
GO:0055014 atrial cardiac muscle cell development
GO:0055015 ventricular cardiac muscle cell development
GO:0060037 pharyngeal system development
GO:0060039 pericardium development

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site
IPR020479 Homeobox domain, metazoaDomainDomain

Diseases

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Interactions

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InteractorPartnerSourcesPublicationsLink