Entity Details

Primary name NPY2R_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP49146
EntryNameNPY2R_HUMAN
FullNameNeuropeptide Y receptor type 2
TaxID9606
Evidenceevidence at protein level
Length381
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesNPY2R

GO terms

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GOName
GO:0001601 peptide YY receptor activity
GO:0001662 behavioral fear response
GO:0002793 positive regulation of peptide secretion
GO:0003151 outflow tract morphogenesis
GO:0003214 cardiac left ventricle morphogenesis
GO:0004983 neuropeptide Y receptor activity
GO:0005246 calcium channel regulator activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005929 cilium
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007263 nitric oxide mediated signal transduction
GO:0007568 aging
GO:0007626 locomotory behavior
GO:0010811 positive regulation of cell-substrate adhesion
GO:0031645 negative regulation of nervous system process
GO:0033603 positive regulation of dopamine secretion
GO:0038023 signaling receptor activity
GO:0043951 negative regulation of cAMP-mediated signaling
GO:0045987 positive regulation of smooth muscle contraction
GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep
GO:0046903 secretion
GO:0051048 negative regulation of secretion
GO:0051930 regulation of sensory perception of pain
GO:0051967 negative regulation of synaptic transmission, glutamatergic
GO:0090394 negative regulation of excitatory postsynaptic potential
GO:0097730 non-motile cilium
GO:2000252 negative regulation of feeding behavior

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000611 Neuropeptide Y receptor familyFamilyFamily
IPR001358 Neuropeptide Y2 receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00847 CysteamineDrugbanksmall molecule
DB05004 Peptide YY (3-36)Drugbanksmall molecule
DB05045 ObinepitideDrugbanksmall molecule