Entity Details

Primary name DHYS_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP49366
EntryNameDHYS_HUMAN
FullNameDeoxyhypusine synthase
TaxID9606
Evidenceevidence at protein level
Length369
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesDHPS

GO terms

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GOName
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006412 translation
GO:0008216 spermidine metabolic process
GO:0008284 positive regulation of cell population proliferation
GO:0008612 peptidyl-lysine modification to peptidyl-hypusine
GO:0034038 deoxyhypusine synthase activity
GO:0042802 identical protein binding

Subcellular Location

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Domains

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DomainNameCategoryType
IPR002773 Deoxyhypusine synthaseFamilyFamily
IPR029035 DHS-like NAD/FAD-binding domain superfamilyFamilyHomologous superfamily
IPR036982 Deoxyhypusine synthase superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB03639 1-Guanidinium-7-AminoheptaneDrugbanksmall molecule

Interactions

24 interactions

InteractorPartnerSourcesPublicationsLink
DHYS_HUMANNIF3L_HUMANBioGRID, HPRD, IntAct16189514 19060904 details
DHYS_HUMANNUD18_HUMANBioGRID, HPRD, IntAct16189514 19060904 details
DHYS_HUMANIF5A2_HUMANBioGRID, HPRD, IntAct16189514 25416956 32296183 details
DHYS_HUMANRL9_HUMANBioGRID, HPRD, IntAct16189514 25416956 28514442 32296183 details
DHYS_HUMANUBE2H_HUMANIntAct19549727 details
DHYS_HUMANMK03_HUMANBioGRID, IntAct23602568 24722188 25852190 26496610 31980649 32296183 details
DHYS_HUMANRB27B_HUMANBioGRID, IntAct25416956 32296183 details
DHYS_HUMANREL_HUMANBioGRID, IntAct25416956 32296183 details
DHYS_HUMANZN138_HUMANBioGRID, IntAct25416956 32296183 details
DHYS_HUMANIF5A1_HUMANBioGRID, HPRD, IntAct10229683 12562768 12788913 25416956 32296183 7929297 details
DHYS_HUMANVASH1_HUMANBioGRID, IntAct25416956 details
DHYS_HUMANNTAQ1_HUMANBioGRID, IntAct25416956 details
DHYS_HUMANPTPRH_HUMANBioGRID, IntAct25416956 details
DHYS_HUMANDHYS_HUMANBioGRID, HPRD, IntAct15100216 25416956 32296183 9493264 details
DHYS_HUMANPAX6_HUMANBioGRID, IntAct32296183 details
DHYS_HUMANRET1_HUMANBioGRID, IntAct32296183 details
DHYS_HUMANLNX1_HUMANBioGRID, IntAct32296183 details
DHYS_HUMANBRCA1_HUMANBioGRID25184681 details
DHYS_HUMANMEOX2_HUMANBioGRID32296183 details
DHYS_HUMANEXOS4_HUMANBioGRID, IntAct27173435 unassigned1312 details
DHYS_HUMANEXOS7_HUMANBioGRID, IntAct27173435 unassigned1312 details
DHYS_HUMANEXOS2_HUMANBioGRID, IntAct27173435 unassigned1312 details
DHYS_HUMANSRRM2_HUMANBioGRID16159877 details
DHYS_HUMANTULP3_HUMANBioGRID33187986 details