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Entity Details
Primary name
RGS7_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
P49802
EntryName
RGS7_HUMAN
FullName
Regulator of G-protein signaling 7
TaxID
9606
Evidence
evidence at protein level
Length
495
SequenceStatus
complete
DateCreated
1996-10-01
DateModified
2021-06-02
Ontological Relatives
Genes
RGS7
GO terms
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GO
Name
GO:0005096
GTPase activator activity
GO:0005829
cytosol
GO:0005886
plasma membrane
GO:0006457
protein folding
GO:0007186
G protein-coupled receptor signaling pathway
GO:0009968
negative regulation of signal transduction
GO:0031681
G-protein beta-subunit binding
GO:0035556
intracellular signal transduction
GO:0043547
positive regulation of GTPase activity
Subcellular Location
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Subcellular Location
Cell membrane
Cytoplasm
Membrane
Domains
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Domain
Name
Category
Type
IPR000591
DEP domain
Domain
Domain
IPR015898
G-protein gamma-like domain
Domain
Domain
IPR016137
RGS domain
Domain
Domain
IPR036284
G-protein gamma-like domain superfamily
Family
Homologous superfamily
IPR036305
RGS domain superfamily
Family
Homologous superfamily
IPR036388
Winged helix-like DNA-binding domain superfamily
Family
Homologous superfamily
IPR036390
Winged helix DNA-binding domain superfamily
Family
Homologous superfamily
IPR040759
Regulator of G-protein signalling, DHEX domain
Domain
Domain
Diseases
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Drugs
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Interactions
22 interactions
Interactor
Partner
Sources
Publications
Link
RGS7_HUMAN
CRK_HUMAN
IntAct
17474147
details
RGS7_HUMAN
PLCG1_HUMAN
IntAct
17474147
details
RGS7_HUMAN
GNB5_HUMAN
BioGRID, HPRD, IntAct
10051672
10339615
10521509
19182865
19376773
26186194
28514442
9789084
details
RGS7_HUMAN
PKD1_HUMAN
BioGRID, HPRD
10339594
details
RGS7_HUMAN
GNAQ_HUMAN
BioGRID, HPRD
12670932
details
RGS7_HUMAN
SNAPN_HUMAN
BioGRID, HPRD
12659861
details
RGS7_HUMAN
ACM3_HUMAN
BioGRID
19182865
details
RGS7_HUMAN
ACM5_HUMAN
BioGRID
19182865
details
RGS7_HUMAN
ACM1_HUMAN
BioGRID
19182865
details
RGS7_HUMAN
ACM2_HUMAN
BioGRID
19182865
details
RGS7_HUMAN
FOS_HUMAN
IntAct
20195357
details
RGS7_HUMAN
HS90B_HUMAN
IntAct
22939624
details
RGS7_HUMAN
GNAI3_HUMAN
BioGRID, HPRD
10092682
details
RGS7_HUMAN
GNAZ_HUMAN
BioGRID, HPRD
10092682
details
RGS7_HUMAN
TCPE_HUMAN
BioGRID
19376773
details
RGS7_HUMAN
HS90A_HUMAN
BioGRID
22939624
details
RGS7_HUMAN
KPCA_HUMAN
HPRD
12077120
details
RGS7_HUMAN
1433B_HUMAN
HPRD
10862767
details
RGS7_HUMAN
GNAI1_HUMAN
HPRD
9572280
details
RGS7_HUMAN
GNAO_HUMAN
HPRD
9572280
details
RGS7_HUMAN
MSX1_HUMAN
HPRD
10862767
details
RGS7_HUMAN
1433T_HUMAN
HPRD
10862767
details
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