Entity Details

Primary name KHK_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP50053
EntryNameKHK_HUMAN
FullNameKetohexokinase
TaxID9606
Evidenceevidence at protein level
Length298
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesKHK

GO terms

Show/Hide Table
GOName
GO:0004454 ketohexokinase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006000 fructose metabolic process
GO:0009744 response to sucrose
GO:0009749 response to glucose
GO:0009750 response to fructose
GO:0010043 response to zinc ion
GO:0032868 response to insulin
GO:0061624 fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
GO:0070062 extracellular exosome
GO:0070873 regulation of glycogen metabolic process

Subcellular Location

Show/Hide Table

Domains

Show/Hide Table
DomainNameCategoryType
IPR011611 Carbohydrate kinase PfkBDomainDomain
IPR029056 Ribokinase-likeFamilyHomologous superfamily
IPR034093 KetohexokinaseFamilyFamily

Diseases

Show/Hide Table
Disease IDSourceNameDescription
229800 OMIMFructosuria (FRUCT)Benign defect of intermediary metabolism. The disease is caused by variants affecting the gene represented in this entry.