Entity Details

Primary name RAB7A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP51149
EntryNameRAB7A_HUMAN
FullNameRas-related protein Rab-7a
TaxID9606
Evidenceevidence at protein level
Length207
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesRAB7A

GO terms

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GOName
GO:0000045 autophagosome assembly
GO:0000421 autophagosome membrane
GO:0003924 GTPase activity
GO:0003925 G protein activity
GO:0005525 GTP binding
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005770 late endosome
GO:0005811 lipid droplet
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006622 protein targeting to lysosome
GO:0006897 endocytosis
GO:0007174 epidermal growth factor catabolic process
GO:0008333 endosome to lysosome transport
GO:0010008 endosome membrane
GO:0015031 protein transport
GO:0016042 lipid catabolic process
GO:0019003 GDP binding
GO:0019076 viral release from host cell
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0022615 protein to membrane docking
GO:0030667 secretory granule membrane
GO:0030670 phagocytic vesicle membrane
GO:0031902 late endosome membrane
GO:0032419 extrinsic component of lysosome membrane
GO:0033162 melanosome membrane
GO:0034054 suppression by symbiont of host defense-related programmed cell death
GO:0042147 retrograde transport, endosome to Golgi
GO:0043312 neutrophil degranulation
GO:0045022 early endosome to late endosome transport
GO:0045335 phagocytic vesicle
GO:0045732 positive regulation of protein catabolic process
GO:0048524 positive regulation of viral process
GO:0061724 lipophagy
GO:0070062 extracellular exosome
GO:0090382 phagosome maturation
GO:0090383 phagosome acidification
GO:0090385 phagosome-lysosome fusion
GO:0099638 endosome to plasma membrane protein transport
GO:1902586 multi-organism intercellular transport
GO:1903542 negative regulation of exosomal secretion
GO:1903543 positive regulation of exosomal secretion
GO:1905366 negative regulation of intralumenal vesicle formation
GO:1905394 retromer complex binding

Subcellular Location

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Subcellular Location
Cytoplasmic vesicle
Endosome membrane
Late endosome membrane
Lipid droplet
Lysosome membrane
Melanosome membrane

Domains

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DomainNameCategoryType
IPR001806 Small GTPaseFamilyFamily
IPR005225 Small GTP-binding protein domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB04315 Guanosine-5'-DiphosphateDrugbanksmall molecule

Interactions

91 interactions

InteractorPartnerSourcesPublicationsLink
RAB7A_HUMANRILP_HUMANBioGRID, DIP, HPRD, IntAct, UniProt11179213 11448994 15933719 18552835 18787122 25080504 25445562 25533187 25908847 26496610 26911690 30721249 32814053 details
RAB7A_HUMANPCNA_HUMANUniProt26030842 details
RAB7A_HUMANOSBL1_HUMANUniProt30721249 details
RAB7A_HUMANCL074_HUMANIntAct32814053 details
RAB7A_HUMANWDR61_HUMANIntAct32814053 details
RAB7A_HUMANATLA1_HUMANIntAct32814053 details
RAB7A_HUMANCHIP_HUMANIntAct32814053 details
RAB7A_HUMANCSN3_HUMANIntAct32814053 details
RAB7A_HUMANID3_HUMANIntAct32814053 details
RAB7A_HUMANRAE1_HUMANBioGRID, HPRD12576024 9563513 details
RAB7A_HUMANRAB17_HUMANBioGRID10329441 details
RAB7A_HUMANRAB4A_HUMANBioGRID10329441 34079125 details
RAB7A_HUMANRAB4B_HUMANBioGRID10329441 details
RAB7A_HUMANRAB5A_HUMANBioGRID10329441 22939629 26344197 34079125 details
RAB7A_HUMANRAB5B_HUMANBioGRID10329441 26344197 details
RAB7A_HUMANRAB6A_HUMANBioGRID10329441 details
RAB7A_HUMANRB22A_HUMANBioGRID10329441 details
RAB7A_HUMANUCHL5_HUMANBioGRID21800051 details
RAB7A_HUMANRN115_HUMANBioGRID, HPRD12972561 details
RAB7A_HUMANKR109_HUMANBioGRID25416956 details
RAB7A_HUMANKR103_HUMANBioGRID25416956 details
RAB7A_HUMANSNX3_HUMANBioGRID24344282 details
RAB7A_HUMANVP26A_HUMANBioGRID24344282 details
RAB7A_HUMANVPS35_HUMANBioGRID24344282 29893854 details
RAB7A_HUMANVPS29_HUMANBioGRID24344282 details
RAB7A_HUMANVPS11_HUMANBioGRID25445562 details
RAB7A_HUMANVPS16_HUMANBioGRID25445562 details
RAB7A_HUMANVPS18_HUMANBioGRID25445562 details
RAB7A_HUMANVPS39_HUMANBioGRID25445562 details
RAB7A_HUMANVPS41_HUMANBioGRID25445562 details
RAB7A_HUMANPRKN_HUMANBioGRID26911690 details
RAB7A_HUMANP53_HUMANBioGRID27229929 details
RAB7A_HUMANPRAF1_HUMANBioGRID, HPRD10329441 29360040 details
RAB7A_HUMANRAB13_HUMANBioGRID21795389 details
RAB7A_HUMANVHL_HUMANIntAct17353931 details
RAB7A_HUMANCRCM_HUMANIntAct17353931 details
RAB7A_HUMANATG5_HUMANIntAct17353931 details
RAB7A_HUMANGBRL2_HUMANIntAct17353931 details
RAB7A_HUMAN3MG_HUMANIntAct17353931 details
RAB7A_HUMANIKKE_HUMANIntAct17353931 details
RAB7A_HUMANTRAF6_HUMANIntAct17353931 details
RAB7A_HUMANAAKB1_HUMANIntAct17353931 details
RAB7A_HUMANHLAB_HUMANIntAct17353931 details
RAB7A_HUMANSH3K1_HUMANMINT20711168 details
RAB7A_HUMANDYN2_HUMANMINT20711168 details
RAB7A_HUMANATG9A_HUMANMINT21169990 details
RAB7A_HUMANGDIA_HUMANBioGRID, IntAct26496610 28514442 29360040 details
RAB7A_HUMANVDAC2_HUMANBioGRID, IntAct26496610 29360040 31536960 details
RAB7A_HUMANZFY27_HUMANDIP25855459 details
RAB7A_HUMANPKHM1_HUMANBioGRID, IntAct27291868 27777970 details
RAB7A_HUMANRHEB_HUMANBioGRID15809346 26344197 details
RAB7A_HUMANPSA7_HUMANBioGRID14998988 details
RAB7A_HUMANLST2_HUMANBioGRID19460345 details
RAB7A_HUMANGLUT4_HUMANBioGRID, HPRD16396496 details
RAB7A_HUMANKCNN4_HUMANBioGRID20720181 details
RAB7A_HUMANAT132_HUMANBioGRID22768177 details
RAB7A_HUMANLEG3_HUMANBioGRID24619419 details
RAB7A_HUMANARL8B_HUMANBioGRID26344197 29360040 details
RAB7A_HUMANGDIB_HUMANBioGRID26344197 29360040 details
RAB7A_HUMANNOTC1_HUMANBioGRID24662486 details
RAB7A_HUMANU2AF2_HUMANBioGRID26641092 details
RAB7A_HUMANTS101_HUMANBioGRID27764233 29859188 details
RAB7A_HUMANCHMP5_HUMANBioGRID27764233 details
RAB7A_HUMANMTSS1_HUMANBioGRID28264927 details
RAB7A_HUMANMON1A_HUMANBioGRID29360040 details
RAB7A_HUMANMON1B_HUMANBioGRID29360040 33144569 details
RAB7A_HUMANCCZ1B_HUMANBioGRID29360040 33144569 details
RAB7A_HUMANCCZ1_HUMANBioGRID29360040 33144569 details
RAB7A_HUMANACSL5_HUMANBioGRID29360040 details
RAB7A_HUMANK1C15_HUMANBioGRID29360040 details
RAB7A_HUMANSPG21_HUMANBioGRID29360040 details
RAB7A_HUMANREEP5_HUMANBioGRID29360040 details
RAB7A_HUMANTOM22_HUMANBioGRID29360040 details
RAB7A_HUMANRMC1_HUMANBioGRID29360040 33144569 details
RAB7A_HUMANRAB7A_HUMANBioGRID29360040 details
RAB7A_HUMANCE051_HUMANBioGRID29360040 details
RAB7A_HUMANPRAF3_HUMANBioGRID29360040 details
RAB7A_HUMANSNG2_HUMANBioGRID29360040 details
RAB7A_HUMANTOM40_HUMANBioGRID29360040 details
RAB7A_HUMANTPD52_HUMANBioGRID29360040 details
RAB7A_HUMANVATA_HUMANBioGRID29360040 details
RAB7A_HUMANESYT1_HUMANBioGRID29360040 details
RAB7A_HUMANUVRAG_HUMANBioGRID25533187 details
RAB7A_HUMANSZT2_HUMANBioGRID28199315 details
RAB7A_HUMANDEFI8_HUMANBioGRID27777970 details
RAB7A_HUMANFLCN_HUMANBioGRID28656962 details
RAB7A_HUMANMLP3A_HUMANBioGRID22496373 details
RAB7A_HUMANNREP_HUMANBioGRID25336651 details
RAB7A_HUMANST7_HUMANBioGRID29395067 details
RAB7A_HUMANNPC1_HUMANBioGRID33144569 details
RAB7A_HUMANPGTB2_HUMANHPRD11591706 details