Entity Details

Primary name PDE6C_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP51160
EntryNamePDE6C_HUMAN
FullNameCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'
TaxID9606
Evidenceevidence at protein level
Length858
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesPDE6C

GO terms

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GOName
GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0005886 plasma membrane
GO:0007165 signal transduction
GO:0007601 visual perception
GO:0007603 phototransduction, visible light
GO:0030553 cGMP binding
GO:0046549 retinal cone cell development
GO:0046872 metal ion binding
GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR002073 3'5'-cyclic nucleotide phosphodiesterase, catalytic domainDomainDomain
IPR003018 GAF domainDomainDomain
IPR003607 HD/PDEase domainDomainDomain
IPR023088 3'5'-cyclic nucleotide phosphodiesteraseFamilyFamily
IPR023174 3'5'-cyclic nucleotide phosphodiesterase, conserved siteSiteConserved site
IPR029016 GAF-like domain superfamilyFamilyHomologous superfamily
IPR036971 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00201 CaffeineDrugbanksmall molecule
DB09283 TrapidilDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PDE6C_HUMANCDC42_HUMANBioGRID31478661 details