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Entity Details
Primary name
SCNNG_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
P51170
EntryName
SCNNG_HUMAN
FullName
Amiloride-sensitive sodium channel subunit gamma
TaxID
9606
Evidence
evidence at protein level
Length
649
SequenceStatus
complete
DateCreated
1996-10-01
DateModified
2021-06-02
Ontological Relatives
Genes
SCNN1G
GO terms
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GO
Name
GO:0005216
ion channel activity
GO:0005272
sodium channel activity
GO:0005654
nucleoplasm
GO:0005886
plasma membrane
GO:0005887
integral component of plasma membrane
GO:0006814
sodium ion transport
GO:0007588
excretion
GO:0009897
external side of plasma membrane
GO:0015280
ligand-gated sodium channel activity
GO:0016324
apical plasma membrane
GO:0034220
ion transmembrane transport
GO:0034706
sodium channel complex
GO:0035725
sodium ion transmembrane transport
GO:0050699
WW domain binding
GO:0050891
multicellular organismal water homeostasis
GO:0050909
sensory perception of taste
GO:0055078
sodium ion homeostasis
GO:0070062
extracellular exosome
GO:0098797
plasma membrane protein complex
GO:1904045
cellular response to aldosterone
Subcellular Location
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Subcellular Location
Apical cell membrane
Domains
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Domain
Name
Category
Type
IPR001873
Epithelial sodium channel
Family
Family
IPR004724
Epithelial sodium channel, chordates
Family
Family
IPR020903
Epithelial sodium channel, conserved site
Site
Conserved site
Diseases
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Drugs
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Drug
Name
Source
Type
DB00384
Triamterene
Drugbank
small molecule
DB00594
Amiloride
Drugbank
small molecule
DB14509
Lithium carbonate
Drugbank
small molecule
Interactions
18 interactions
Interactor
Partner
Sources
Publications
Link
SCNNG_HUMAN
NEDD4_HUMAN
BioGRID, HPRD, MINT
10212229
10642508
11244092
11359767
12167593
17013377
9351815
details
SCNNG_HUMAN
STX1A_HUMAN
BioGRID, HPRD
10409621
12562778
14996668
details
SCNNG_HUMAN
WWP2_HUMAN
BioGRID, HPRD
12167593
details
SCNNG_HUMAN
NED4L_HUMAN
BioGRID, HPRD
11244092
11802777
12876068
15328345
16416336
16716084
16844684
18322022
18498246
details
SCNNG_HUMAN
EPN1_HUMAN
BioGRID
16574660
details
SCNNG_HUMAN
SCNNB_HUMAN
BioGRID, HPRD
22526458
8986818
details
SCNNG_HUMAN
SERP1_HUMAN
BioGRID
22526458
details
SCNNG_HUMAN
SOX4_HUMAN
BioGRID
25969425
details
SCNNG_HUMAN
COMDA_HUMAN
BioGRID
29997525
details
SCNNG_HUMAN
COMD1_HUMAN
BioGRID, IntAct
14645214
details
SCNNG_HUMAN
SCNNA_HUMAN
BioGRID, HPRD, IntAct
10409621
16423824
21775436
27903760
details
SCNNG_HUMAN
SCNNG_HUMAN
IntAct
21775436
details
SCNNG_HUMAN
SCNND_HUMAN
HPRD, IntAct
16423824
7499195
details
SCNNG_HUMAN
AP1M2_HUMAN
BioGRID
17381423
details
SCNNG_HUMAN
UBP2_HUMAN
BioGRID
18701608
21478478
details
SCNNG_HUMAN
UBP8_HUMAN
BioGRID
23297398
details
SCNNG_HUMAN
MK01_HUMAN
HPRD
11805112
details
SCNNG_HUMAN
UBP10_HUMAN
HPRD
18632802
details
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