Entity Details

Primary name AK1D1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP51857
EntryNameAK1D1_HUMAN
FullNameAldo-keto reductase family 1 member D1
TaxID9606
Evidenceevidence at protein level
Length326
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesAKR1D1

GO terms

Show/Hide Table
GOName
GO:0004032 alditol:NADP+ 1-oxidoreductase activity
GO:0005496 steroid binding
GO:0005829 cytosol
GO:0006699 bile acid biosynthetic process
GO:0006707 cholesterol catabolic process
GO:0007586 digestion
GO:0008202 steroid metabolic process
GO:0008207 C21-steroid hormone metabolic process
GO:0008209 androgen metabolic process
GO:0016229 steroid dehydrogenase activity
GO:0030573 bile acid catabolic process
GO:0047086 ketosteroid monooxygenase activity
GO:0047787 delta4-3-oxosteroid 5beta-reductase activity
GO:0047834 D-threo-aldose 1-dehydrogenase activity

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR018170 Aldo/keto reductase, conserved siteSiteConserved site
IPR020471 Aldo-keto reductaseFamilyFamily
IPR023210 NADP-dependent oxidoreductase domainDomainDomain
IPR036812 NADP-dependent oxidoreductase domain superfamilyFamilyHomologous superfamily
IPR044483 Aldo-keto reductase family 1 member D1FamilyFamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB00548 Azelaic acidDrugbanksmall molecule
DB00717 NorethisteroneDrugbanksmall molecule
DB00741 HydrocortisoneDrugbanksmall molecule
DB01216 FinasterideDrugbanksmall molecule
DB06077 LumateperoneDrugbanksmall molecule
DB07447 5beta-dihydrotestosteroneDrugbanksmall molecule
DB07557 3,20-PregnanedioneDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink