Entity Details

Primary name FGF8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP55075
EntryNameFGF8_HUMAN
FullNameFibroblast growth factor 8
TaxID9606
Evidenceevidence at protein level
Length233
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesFGF8

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0001569 branching involved in blood vessel morphogenesis
GO:0001656 metanephros development
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0001759 organ induction
GO:0001823 mesonephros development
GO:0001839 neural plate morphogenesis
GO:0001934 positive regulation of protein phosphorylation
GO:0001947 heart looping
GO:0001974 blood vessel remodeling
GO:0003007 heart morphogenesis
GO:0003148 outflow tract septum morphogenesis
GO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0005104 fibroblast growth factor receptor binding
GO:0005105 type 1 fibroblast growth factor receptor binding
GO:0005111 type 2 fibroblast growth factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0006979 response to oxidative stress
GO:0007369 gastrulation
GO:0008045 motor neuron axon guidance
GO:0008078 mesodermal cell migration
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0008406 gonad development
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0009653 anatomical structure morphogenesis
GO:0009887 animal organ morphogenesis
GO:0009897 external side of plasma membrane
GO:0009953 dorsal/ventral pattern formation
GO:0010628 positive regulation of gene expression
GO:0014070 response to organic cyclic compound
GO:0021543 pallium development
GO:0021544 subpallium development
GO:0021798 forebrain dorsal/ventral pattern formation
GO:0021846 cell proliferation in forebrain
GO:0021884 forebrain neuron development
GO:0023019 signal transduction involved in regulation of gene expression
GO:0030154 cell differentiation
GO:0030182 neuron differentiation
GO:0030334 regulation of cell migration
GO:0030539 male genitalia development
GO:0030878 thyroid gland development
GO:0030916 otic vesicle formation
GO:0030917 midbrain-hindbrain boundary development
GO:0033563 dorsal/ventral axon guidance
GO:0035050 embryonic heart tube development
GO:0035108 limb morphogenesis
GO:0035116 embryonic hindlimb morphogenesis
GO:0035909 aorta morphogenesis
GO:0042056 chemoattractant activity
GO:0042476 odontogenesis
GO:0042487 regulation of odontogenesis of dentin-containing tooth
GO:0042493 response to drug
GO:0043524 negative regulation of neuron apoptotic process
GO:0045165 cell fate commitment
GO:0045597 positive regulation of cell differentiation
GO:0045745 positive regulation of G protein-coupled receptor signaling pathway
GO:0045840 positive regulation of mitotic nuclear division
GO:0046622 positive regulation of organ growth
GO:0048702 embryonic neurocranium morphogenesis
GO:0048853 forebrain morphogenesis
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0051781 positive regulation of cell division
GO:0051897 positive regulation of protein kinase B signaling
GO:0055026 negative regulation of cardiac muscle tissue development
GO:0060037 pharyngeal system development
GO:0060128 corticotropin hormone secreting cell differentiation
GO:0060129 thyroid-stimulating hormone-secreting cell differentiation
GO:0060348 bone development
GO:0060425 lung morphogenesis
GO:0060445 branching involved in salivary gland morphogenesis
GO:0060563 neuroepithelial cell differentiation
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071542 dopaminergic neuron differentiation
GO:0090134 cell migration involved in mesendoderm migration
GO:0120223 larynx morphogenesis

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR002209 Fibroblast growth factor familyFamilyFamily
IPR008996 Cytokine IL1/FGFFamilyHomologous superfamily
IPR028249 Fibroblast growth factor 8FamilyFamily

Diseases

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Interactions

5 interactions