Entity Details

Primary name CCL18_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP55774
EntryNameCCL18_HUMAN
FullNameC-C motif chemokine 18
TaxID9606
Evidenceevidence at protein level
Length89
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesCCL18

GO terms

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GOName
GO:0002548 monocyte chemotaxis
GO:0005615 extracellular space
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007154 cell communication
GO:0007165 signal transduction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007267 cell-cell signaling
GO:0008009 chemokine activity
GO:0030593 neutrophil chemotaxis
GO:0031640 killing of cells of other organism
GO:0043547 positive regulation of GTPase activity
GO:0048020 CCR chemokine receptor binding
GO:0048247 lymphocyte chemotaxis
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
GO:0070098 chemokine-mediated signaling pathway
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071346 cellular response to interferon-gamma
GO:0071347 cellular response to interleukin-1
GO:0071356 cellular response to tumor necrosis factor

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000827 CC chemokine, conserved siteSiteConserved site
IPR001811 Chemokine interleukin-8-like domainDomainDomain
IPR036048 Chemokine interleukin-8-like superfamilyFamilyHomologous superfamily
IPR039809 Chemokine beta/gamma/deltaFamilyFamily

Diseases

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Interactions

8 interactions

InteractorPartnerSourcesPublicationsLink
CCL18_HUMANEF1A1_HUMANBioGRID, HPRD, IntAct16169070 details
CCL18_HUMANDPYL1_HUMANBioGRID, HPRD, IntAct16169070 details
CCL18_HUMANP53_HUMANBioGRID, HPRD, IntAct16169070 details
CCL18_HUMANU119A_HUMANBioGRID, HPRD, IntAct16169070 details
CCL18_HUMANTLE1_HUMANBioGRID, HPRD, IntAct16169070 details
CCL18_HUMANERG28_HUMANBioGRID, HPRD, IntAct16169070 details
CCL18_HUMANPITM3_HUMANIntAct21481794 details
CCL18_HUMANCCL11_HUMANbhf-ucl, BioGRID28381538 details