Entity Details

Primary name RS27A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP62979
EntryNameRS27A_HUMAN
FullNameUbiquitin-40S ribosomal protein S27a
TaxID9606
Evidenceevidence at protein level
Length156
SequenceStatuscomplete
DateCreated2004-08-31
DateModified2021-06-02

Ontological Relatives

GenesRPS27A

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000187 obsolete activation of MAPK activity
GO:0000209 protein polyubiquitination
GO:0000715 nucleotide-excision repair, DNA damage recognition
GO:0000717 nucleotide-excision repair, DNA duplex unwinding
GO:0002181 cytoplasmic translation
GO:0002753 cytoplasmic pattern recognition receptor signaling pathway
GO:0002755 MyD88-dependent toll-like receptor signaling pathway
GO:0002756 MyD88-independent toll-like receptor signaling pathway
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005741 mitochondrial outer membrane
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006294 nucleotide-excision repair, preincision complex assembly
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0006297 nucleotide-excision repair, DNA gap filling
GO:0006412 translation
GO:0006413 translational initiation
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0007096 regulation of exit from mitosis
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0007254 JNK cascade
GO:0008104 protein localization
GO:0010008 endosome membrane
GO:0015935 small ribosomal subunit
GO:0016020 membrane
GO:0016055 Wnt signaling pathway
GO:0016197 endosomal transport
GO:0016567 protein ubiquitination
GO:0016579 protein deubiquitination
GO:0019058 viral life cycle
GO:0019068 virion assembly
GO:0019081 viral translation
GO:0019083 viral transcription
GO:0019221 cytokine-mediated signaling pathway
GO:0019941 modification-dependent protein catabolic process
GO:0019985 translesion synthesis
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030666 endocytic vesicle membrane
GO:0031145 anaphase-promoting complex-dependent catabolic process
GO:0031386 protein tag
GO:0031625 ubiquitin protein ligase binding
GO:0031982 vesicle
GO:0033683 nucleotide-excision repair, DNA incision
GO:0035666 TRIF-dependent toll-like receptor signaling pathway
GO:0035973 aggrephagy
GO:0036297 interstrand cross-link repair
GO:0036388 pre-replicative complex assembly
GO:0042276 error-prone translesion synthesis
GO:0042769 DNA damage response, detection of DNA damage
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043488 regulation of mRNA stability
GO:0043657 host cell
GO:0044322 endoplasmic reticulum quality control compartment
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051403 stress-activated MAPK cascade
GO:0052031 modulation by symbiont of host defense response
GO:0055085 transmembrane transport
GO:0061024 membrane organization
GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0070062 extracellular exosome
GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway
GO:0070498 interleukin-1-mediated signaling pathway
GO:0070911 global genome nucleotide-excision repair
GO:0070987 error-free translesion synthesis
GO:0075733 intracellular transport of virus
GO:1904380 endoplasmic reticulum mannose trimming
GO:1990000 amyloid fibril formation

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000626 Ubiquitin-like domainDomainDomain
IPR002906 Ribosomal protein S27aDomainDomain
IPR011332 Zinc-binding ribosomal proteinFamilyHomologous superfamily
IPR019954 Ubiquitin conserved siteSiteConserved site
IPR019956 Ubiquitin domainDomainDomain
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR038582 S27a-like superfamilyFamilyHomologous superfamily

Diseases

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Interactions

49 interactions

InteractorPartnerSourcesPublicationsLink
RS27A_HUMANDAZP2_HUMANBioGRID, HPRD, IntAct16189514 25416956 32296183 details
RS27A_HUMANDESI1_HUMANBioGRID, IntAct32296183 details
RS27A_HUMANKANL3_HUMANHPRD, IntAct16169070 details
RS27A_HUMANPLS4_HUMANBioGRID, IntAct32296183 details
RS27A_HUMANTRAF6_HUMANBioGRID, IntAct14743216 28024152 details
RS27A_HUMANMDM2_HUMANBioGRID, IntAct21561866 21988832 details
RS27A_HUMANLITAF_HUMANBioGRID, IntAct32296183 details
RS27A_HUMANMTURN_HUMANBioGRID, IntAct32296183 details
RS27A_HUMANUBQL2_HUMANBioGRID, IntAct32296183 details
RS27A_HUMANSMAD2_HUMANBioGRID, HPRD15231748 15761153 details
RS27A_HUMANDNJB2_HUMANBioGRID, HPRD15936278 33957083 details
RS27A_HUMANWFS1_HUMANIntAct32814053 details
RS27A_HUMANFSHR_HUMANHPRD12960054 details
RS27A_HUMANUBQL1_HUMANBioGRID, IntAct32296183 details
RS27A_HUMANRNF11_HUMANBioGRID, HPRD, IntAct14755250 15231748 31985874 32814053 details
RS27A_HUMANHSPB1_HUMANIntAct32814053 details
RS27A_HUMANGGA3_HUMANHPRD15039775 details
RS27A_HUMANCD11B_HUMANBioGRID, IntAct21988832 details
RS27A_HUMANCACO2_HUMANBioGRID, IntAct25416956 details
RS27A_HUMANPKHB2_HUMANBioGRID, IntAct32296183 details
RS27A_HUMANPAXI1_HUMANBioGRID21163940 details
RS27A_HUMANA4_HUMANBioGRID21832049 details
RS27A_HUMANF168A_HUMANBioGRID, IntAct32296183 details
RS27A_HUMANPTEN_HUMANBioGRID26561776 30631154 details
RS27A_HUMANHD_HUMANIntAct32814053 details
RS27A_HUMANEPN3_HUMANBioGRID32296183 details
RS27A_HUMANRD23A_HUMANBioGRID, IntAct32296183 details
RS27A_HUMANZ512B_HUMANBioGRID15231748 details
RS27A_HUMANWBP2_HUMANBioGRID27578003 details
RS27A_HUMANP53_HUMANBioGRID, MINT21561866 22653443 details
RS27A_HUMANRS27A_HUMANBioGRID, HPRD11733996 28292943 details
RS27A_HUMANSMUF1_HUMANHPRD15761153 details
RS27A_HUMANMAST2_HUMANHPRD14764729 details
RS27A_HUMANSMAD1_HUMANHPRD15761153 details
RS27A_HUMANTGFR1_HUMANHPRD15761153 details
RS27A_HUMANCDC6_HUMANHPRD10995389 details
RS27A_HUMANFMR1_HUMANIntAct31413325 details
RS27A_HUMANM3K3_HUMANIntAct14743216 details
RS27A_HUMANACVR1_HUMANHPRD15761153 details
RS27A_HUMANTNR1A_HUMANIntAct14743216 details
RS27A_HUMANSMUF2_HUMANHPRD14755250 details
RS27A_HUMANRABX5_HUMANHPRD15143060 details
RS27A_HUMANPOLH_HUMANHPRD17304240 details
RS27A_HUMANSMAD4_HUMANHPRD15761153 details
RS27A_HUMANITA4_HUMANBioGRID22623428 details
RS27A_HUMANGGA1_HUMANHPRD15143060 details
RS27A_HUMANCYH1_HUMANDIP29420262 details
RS27A_HUMANGAN_HUMANBioGRID26460568 details
RS27A_HUMANBMR1B_HUMANHPRD15761153 details