Entity Details

Primary name TNNC1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP63316
EntryNameTNNC1_HUMAN
FullNameTroponin C, slow skeletal and cardiac muscles
TaxID9606
Evidenceevidence at protein level
Length161
SequenceStatuscomplete
DateCreated1987-08-13
DateModified2021-06-02

Ontological Relatives

GenesTNNC1

GO terms

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GOName
GO:0002086 diaphragm contraction
GO:0003009 skeletal muscle contraction
GO:0005509 calcium ion binding
GO:0005829 cytosol
GO:0005861 troponin complex
GO:0006937 regulation of muscle contraction
GO:0010038 response to metal ion
GO:0014883 transition between fast and slow fiber
GO:0030049 muscle filament sliding
GO:0031013 troponin I binding
GO:0031014 troponin T binding
GO:0032972 regulation of muscle filament sliding speed
GO:0042803 protein homodimerization activity
GO:0043462 regulation of ATPase activity
GO:0048306 calcium-dependent protein binding
GO:0051015 actin filament binding
GO:0055010 ventricular cardiac muscle tissue morphogenesis
GO:0060048 cardiac muscle contraction
GO:1990584 cardiac Troponin complex

Subcellular Location

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Domains

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DomainNameCategoryType
IPR002048 EF-hand domainDomainDomain
IPR011992 EF-hand domain pairFamilyHomologous superfamily
IPR018247 EF-Hand 1, calcium-binding siteSiteBinding site

Diseases

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Drugs

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DrugNameSourceType
DB00831 TrifluoperazineDrugbanksmall molecule
DB00922 LevosimendanDrugbanksmall molecule
DB01023 FelodipineDrugbanksmall molecule
DB01244 BepridilDrugbanksmall molecule
DB01373 CalciumDrugbanksmall molecule
DB01375 Aluminium monostearateDrugbanksmall molecule
DB03944 5-[1-(3,4-Dimethoxy-Benzoyl)-1,2,3,4-Tetrahydro-Quinolin-6-Yl]-6-Methyl-3,6-Dihydro-[1,3,4]Thiadiazin-2-OneDrugbanksmall molecule
DB04513 N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideDrugbanksmall molecule