Entity Details

Primary name HBB_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP68871
EntryNameHBB_HUMAN
FullNameHemoglobin subunit beta
TaxID9606
Evidenceevidence at protein level
Length147
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesHBB

GO terms

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GOName
GO:0005344 oxygen carrier activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005829 cytosol
GO:0005833 hemoglobin complex
GO:0006898 receptor-mediated endocytosis
GO:0007596 blood coagulation
GO:0008217 regulation of blood pressure
GO:0010942 positive regulation of cell death
GO:0015671 oxygen transport
GO:0015701 bicarbonate transport
GO:0019825 oxygen binding
GO:0020037 heme binding
GO:0030185 nitric oxide transport
GO:0030492 hemoglobin binding
GO:0031721 hemoglobin alpha binding
GO:0031838 haptoglobin-hemoglobin complex
GO:0042542 response to hydrogen peroxide
GO:0042744 hydrogen peroxide catabolic process
GO:0043177 organic acid binding
GO:0043312 neutrophil degranulation
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0046872 metal ion binding
GO:0070062 extracellular exosome
GO:0070293 renal absorption
GO:0070527 platelet aggregation
GO:0071682 endocytic vesicle lumen
GO:0072562 blood microparticle
GO:0098869 cellular oxidant detoxification
GO:1904724 tertiary granule lumen
GO:1904813 ficolin-1-rich granule lumen

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000971 GlobinDomainDomain
IPR002337 Haemoglobin, beta-typeFamilyFamily
IPR009050 Globin-like superfamilyFamilyHomologous superfamily
IPR012292 Globin/ProtoglobinFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00893 Iron DextranDrugbanksmall molecule
DB01593 ZincDrugbanksmall molecule
DB02126 4-Carboxycinnamic AcidDrugbanksmall molecule
DB06154 Pentaerythritol tetranitrateDrugbanksmall molecule
DB07427 2-[(2-methoxy-5-methylphenoxy)methyl]pyridineDrugbanksmall molecule
DB07428 4-[(5-methoxy-2-methylphenoxy)methyl]pyridineDrugbanksmall molecule
DB07645 Sebacic acidDrugbanksmall molecule
DB08077 2-[4-({[(3,5-DICHLOROPHENYL)AMINO]CARBONYL}AMINO)PHENOXY]-2-METHYLPROPANOIC ACIDDrugbanksmall molecule
DB08262 2,6-dicarboxynaphthaleneDrugbanksmall molecule
DB08486 EfaproxiralDrugbanksmall molecule
DB08632 Trimesic acidDrugbanksmall molecule
DB09112 Nitrous acidDrugbanksmall molecule
DB09130 CopperDrugbanksmall molecule
DB09140 OxygenDrugbanksmall molecule
DB09147 Ferric pyrophosphateDrugbanksmall molecule
DB09517 Sodium ferric gluconate complexDrugbanksmall molecule
DB13995 Ferric pyrophosphate citrateDrugbanksmall molecule
DB14487 Zinc acetateDrugbanksmall molecule
DB14533 Zinc chlorideDrugbanksmall molecule
DB14548 Zinc sulfate, unspecified formDrugbanksmall molecule