Entity Details

Primary name IRX4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP78413
EntryNameIRX4_HUMAN
FullNameIroquois-class homeodomain protein IRX-4
TaxID9606
Evidenceevidence at protein level
Length519
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesIRX4

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007507 heart development
GO:0030182 neuron differentiation
GO:0048468 cell development
GO:0048561 establishment of animal organ orientation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR003893 Iroquois-class homeodomain proteinDomainDomain
IPR008422 Homeobox KN domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
IRX4_HUMANPO6F2_HUMANBioGRID, IntAct32296183 details
IRX4_HUMANRARA_HUMANBioGRID, HPRD11382777 details