Entity Details
| Primary name |
BAT1_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | P82251 |
| EntryName | BAT1_HUMAN |
| FullName | b(0,+)-type amino acid transporter 1 |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 487 |
| SequenceStatus | complete |
| DateCreated | 2001-01-24 |
| DateModified | 2021-06-02 |
Subcellular Location
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| Subcellular Location |
| Apical cell membrane |
Domains
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| Domain | Name | Category | Type |
| IPR002293 | Amino acid/polyamine transporter I | Family | Family |
Diseases
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| Disease ID | Source | Name | Description |
| 220100 | OMIM | Cystinuria (CSNU) | An autosomal disorder characterized by impaired epithelial cell transport of cystine and dibasic amino acids (lysine, ornithine, and arginine) in the proximal renal tubule and gastrointestinal tract. The impaired renal reabsorption of cystine and its low solubility causes the formation of calculi in the urinary tract, resulting in obstructive uropathy, pyelonephritis, and, rarely, renal failure. The disease is caused by variants affecting the gene represented in this entry. |
Drugs
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| Drug | Name | Source | Type |
| DB00130 | L-Glutamine | Drugbank | small molecule |
| DB00138 | Cystine | Drugbank | small molecule |
Interactions
3 interactions