Entity Details

Primary name TFAP4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ01664
EntryNameTFAP4_HUMAN
FullNameTranscription factor AP-4
TaxID9606
Evidenceevidence at protein level
Length338
SequenceStatuscomplete
DateCreated1993-10-01
DateModified2021-06-02

Ontological Relatives

GenesTFAP4

GO terms

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GOName
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0008285 negative regulation of cell population proliferation
GO:0010629 negative regulation of gene expression
GO:0017053 transcription repressor complex
GO:0042803 protein homodimerization activity
GO:0042826 histone deacetylase binding
GO:0043065 positive regulation of apoptotic process
GO:0043392 negative regulation of DNA binding
GO:0043565 sequence-specific DNA binding
GO:0043922 negative regulation by host of viral transcription
GO:0043923 positive regulation by host of viral transcription
GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0065003 protein-containing complex assembly
GO:0070888 E-box binding
GO:0071549 cellular response to dexamethasone stimulus
GO:1901990 regulation of mitotic cell cycle phase transition
GO:1990837 sequence-specific double-stranded DNA binding
GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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