Entity Details

Primary name CP4AB_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ02928
EntryNameCP4AB_HUMAN
FullNameCytochrome P450 4A11
TaxID9606
Evidenceevidence at protein level
Length519
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesCYP4A11

GO terms

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GOName
GO:0001676 long-chain fatty acid metabolic process
GO:0001822 kidney development
GO:0003091 renal water homeostasis
GO:0003095 pressure natriuresis
GO:0005506 iron ion binding
GO:0005737 cytoplasm
GO:0005789 endoplasmic reticulum membrane
GO:0006631 fatty acid metabolic process
GO:0006691 leukotriene metabolic process
GO:0008391 arachidonic acid monooxygenase activity
GO:0008392 arachidonic acid epoxygenase activity
GO:0016324 apical plasma membrane
GO:0018685 alkane 1-monooxygenase activity
GO:0019222 regulation of metabolic process
GO:0019369 arachidonic acid metabolic process
GO:0019373 epoxygenase P450 pathway
GO:0020037 heme binding
GO:0031408 oxylipin biosynthetic process
GO:0032305 positive regulation of icosanoid secretion
GO:0043231 intracellular membrane-bounded organelle
GO:0043651 linoleic acid metabolic process
GO:0046456 icosanoid biosynthetic process
GO:0048252 lauric acid metabolic process
GO:0050051 leukotriene-B4 20-monooxygenase activity
GO:0055078 sodium ion homeostasis
GO:0070330 aromatase activity
GO:0097267 omega-hydroxylase P450 pathway
GO:0102033 long-chain fatty acid omega-hydroxylase activity

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Microsome membrane

Domains

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DomainNameCategoryType
IPR001128 Cytochrome P450FamilyFamily
IPR002401 Cytochrome P450, E-class, group IFamilyFamily
IPR017972 Cytochrome P450, conserved siteSiteConserved site
IPR036396 Cytochrome P450 superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00082 PegvisomantDrugbankbiotech
DB00157 NADHDrugbanksmall molecule
DB00515 CisplatinDrugbanksmall molecule
DB00636 ClofibrateDrugbanksmall molecule
DB00738 PentamidineDrugbanksmall molecule
DB00755 TretinoinDrugbanksmall molecule
DB00898 EthanolDrugbanksmall molecule
DB01234 DexamethasoneDrugbanksmall molecule
DB04977 PlitidepsinSwissprotsmall molecule
DB11077 Polyethylene glycol 400Drugbanksmall molecule
DB11156 PyrantelDrugbanksmall molecule
DB13125 LusutrombopagDrugbanksmall molecule
DB14004 TildrakizumabDrugbankbiotech
DB14649 Dexamethasone acetateDrugbanksmall molecule

Interactions

3 interactions