Entity Details

Primary name EMX2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ04743
EntryNameEMX2_HUMAN
FullNameHomeobox protein EMX2
TaxID9606
Evidenceevidence at protein level
Length252
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GenesEMX2

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007417 central nervous system development
GO:0007420 brain development
GO:0009952 anterior/posterior pattern specification
GO:0021542 dentate gyrus development
GO:0021796 cerebral cortex regionalization
GO:0021846 cell proliferation in forebrain
GO:0021885 forebrain cell migration
GO:0030182 neuron differentiation
GO:0042493 response to drug
GO:0072197 ureter morphogenesis
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000047 Helix-turn-helix motifSiteConserved site
IPR001356 Homeobox domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site
IPR020479 Homeobox domain, metazoaDomainDomain

Diseases

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Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
EMX2_HUMANOTU6A_HUMANBioGRID, IntAct32296183 details
EMX2_HUMANTF2AY_HUMANBioGRID, IntAct20211142 details
EMX2_HUMANMEIS1_HUMANBioGRID, IntAct20211142 details
EMX2_HUMANTLE2_HUMANBioGRID, IntAct20211142 details
EMX2_HUMANIF4E_HUMANHPRD, IntAct15247416 details
EMX2_HUMANH4_HUMANBioGRID, IntAct30021884 details