Entity Details

Primary name BPTF_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ12830
EntryNameBPTF_HUMAN
FullNameNucleosome-remodeling factor subunit BPTF
TaxID9606
Evidenceevidence at protein level
Length3046
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesBPTF

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001892 embryonic placenta development
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006338 chromatin remodeling
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007420 brain development
GO:0007492 endoderm development
GO:0008134 transcription factor binding
GO:0009611 response to wounding
GO:0009952 anterior/posterior pattern specification
GO:0016589 NURF complex
GO:0030425 dendrite
GO:0035064 methylated histone binding
GO:0042766 nucleosome mobilization
GO:0043565 sequence-specific DNA binding
GO:0044297 cell body
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular exosome
GO:1990090 cellular response to nerve growth factor stimulus

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001487 BromodomainDomainDomain
IPR001965 Zinc finger, PHD-typeDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR018359 Bromodomain, conserved siteSiteConserved site
IPR018501 DDT domainDomainDomain
IPR019786 Zinc finger, PHD-type, conserved siteSiteConserved site
IPR019787 Zinc finger, PHD-fingerDomainDomain
IPR028941 WHIM2 domainDomainDomain
IPR036427 Bromodomain-like superfamilyFamilyHomologous superfamily
IPR038028 Nucleosome-remodeling factor subunit BPTFFamilyFamily

Diseases

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