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Entity Details
Primary name
NPC2
Entity type
gene
Source
Source Link
Details
PrimaryID
10577
RefseqGene
NG_007117
Symbol
NPC2
Name
NPC intracellular cholesterol transporter 2
Chromosome
14
Location
14q24.3
TaxID
9606
Status
live
SourceGenome
genomic
SourceOrigin
natural
CreationDate
2001-05-14
ModificationDate
2021-06-11
Ontological Relatives
UniProt IDs
NPC2_HUMAN
GO terms
Show/Hide Table
GO
Name
GO:0005576
extracellular region
GO:0005615
extracellular space
GO:0005764
lysosome
GO:0005783
endoplasmic reticulum
GO:0008203
cholesterol metabolic process
GO:0009615
response to virus
GO:0015485
cholesterol binding
GO:0015914
phospholipid transport
GO:0015918
sterol transport
GO:0019747
regulation of isoprenoid metabolic process
GO:0019899
enzyme binding
GO:0030301
cholesterol transport
GO:0032366
intracellular sterol transport
GO:0032367
intracellular cholesterol transport
GO:0032934
sterol binding
GO:0033344
cholesterol efflux
GO:0034383
low-density lipoprotein particle clearance
GO:0035578
azurophil granule lumen
GO:0042632
cholesterol homeostasis
GO:0043202
lysosomal lumen
GO:0043312
neutrophil degranulation
GO:0046836
glycolipid transport
GO:0070062
extracellular exosome
GO:0120020
cholesterol transfer activity
Diseases
Show/Hide Table
Interactions
29 interactions
Interactor
Partner
Sources
Publications
Link
NPC2
NPC1
IntAct, UniProt
20674861
27238017
details
NPC2
NEGR1
IntAct
27940359
details
NPC2
DHDDS
BioGRID, HPRD
15110773
details
NPC2
NEDD4L
BioGRID
19664597
details
NPC2
USP4
BioGRID
23022198
details
NPC2
BARD1
BioGRID
22990118
details
NPC2
BRCA1
BioGRID
22990118
details
NPC2
ECT2
BioGRID
22990118
details
NPC2
LIG4
BioGRID
22990118
details
NPC2
PAXIP1
BioGRID
22990118
details
NPC2
ERRFI1
BioGRID
20351267
details
NPC2
TRIM14
BioGRID
29053956
details
NPC2
TMPRSS11B
BioGRID, IntAct
28514442
details
NPC2
DEFA1
BioGRID, IntAct
28514442
details
NPC2
DEFA1B
IntAct
28514442
details
NPC2
LDB3
BioGRID, IntAct
26186194
28514442
details
NPC2
IRGQ
BioGRID, IntAct
28514442
details
NPC2
HK3
BioGRID, IntAct
28514442
details
NPC2
TTR
BioGRID, IntAct
28514442
details
NPC2
CFB
BioGRID, IntAct
28514442
details
NPC2
LRP1
BioGRID, IntAct
28514442
details
NPC2
PSG1
BioGRID, IntAct
28514442
details
NPC2
RRAGA
BioGRID, IntAct
26186194
28514442
details
NPC2
TRIM24
BioGRID, MINT
24981860
details
NPC2
SLC9A3R2
BioGRID
22939629
details
NPC2
NDUFV2
BioGRID
22939629
details
NPC2
NUDT19
BioGRID
22939629
details
NPC2
NME2
BioGRID
28514442
details
NPC2
BCAR1
BioGRID
33001583
details
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