Entity Details

Primary name FOXF1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ12946
EntryNameFOXF1_HUMAN
FullNameForkhead box protein F1
TaxID9606
Evidenceevidence at transcript level
Length379
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesFOXF1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001568 blood vessel development
GO:0001570 vasculogenesis
GO:0001701 in utero embryonic development
GO:0001756 somitogenesis
GO:0001763 morphogenesis of a branching structure
GO:0002053 positive regulation of mesenchymal cell proliferation
GO:0003197 endocardial cushion development
GO:0003214 cardiac left ventricle morphogenesis
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007224 smoothened signaling pathway
GO:0007368 determination of left/right symmetry
GO:0007494 midgut development
GO:0007507 heart development
GO:0009887 animal organ morphogenesis
GO:0010811 positive regulation of cell-substrate adhesion
GO:0014822 detection of wounding
GO:0030198 extracellular matrix organization
GO:0030323 respiratory tube development
GO:0030324 lung development
GO:0030335 positive regulation of cell migration
GO:0031016 pancreas development
GO:0043305 negative regulation of mast cell degranulation
GO:0043565 sequence-specific DNA binding
GO:0045198 establishment of epithelial cell apical/basal polarity
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048286 lung alveolus development
GO:0048371 lateral mesodermal cell differentiation
GO:0048557 embryonic digestive tract morphogenesis
GO:0048565 digestive tract development
GO:0048613 embryonic ectodermal digestive tract morphogenesis
GO:0048617 embryonic foregut morphogenesis
GO:0050728 negative regulation of inflammatory response
GO:0051145 smooth muscle cell differentiation
GO:0060426 lung vasculature development
GO:0060438 trachea development
GO:0060441 epithelial tube branching involved in lung morphogenesis
GO:0060461 right lung morphogenesis
GO:0060463 lung lobe morphogenesis
GO:0060841 venous blood vessel development
GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development
GO:0071345 cellular response to cytokine stimulus
GO:0071407 cellular response to organic cyclic compound
GO:0072189 ureter development
GO:0090131 mesenchyme migration
GO:0097070 ductus arteriosus closure
GO:0098609 cell-cell adhesion

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001766 Fork head domainDomainDomain
IPR018122 Fork head domain conserved site1SiteConserved site
IPR030456 Fork head domain conserved site 2SiteConserved site
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
FOXF1_HUMANAURKA_HUMANBioGRID28218735 details
FOXF1_HUMANFANCM_HUMANBioGRID26625197 details