Entity Details

Primary name ANK3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ12955
EntryNameANK3_HUMAN
FullNameAnkyrin-3
TaxID9606
Evidenceevidence at protein level
Length4377
SequenceStatuscomplete
DateCreated2002-07-11
DateModified2021-06-02

Ontological Relatives

GenesANK3

GO terms

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GOName
GO:0000281 mitotic cytokinesis
GO:0005200 structural constituent of cytoskeleton
GO:0005764 lysosome
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0007009 plasma membrane organization
GO:0007165 signal transduction
GO:0007409 axonogenesis
GO:0007528 neuromuscular junction development
GO:0008092 cytoskeletal protein binding
GO:0008093 cytoskeletal anchor activity
GO:0009925 basal plasma membrane
GO:0009986 cell surface
GO:0010628 positive regulation of gene expression
GO:0010650 positive regulation of cell communication by electrical coupling
GO:0010765 positive regulation of sodium ion transport
GO:0010960 magnesium ion homeostasis
GO:0014704 intercalated disc
GO:0014731 spectrin-associated cytoskeleton
GO:0016323 basolateral plasma membrane
GO:0016328 lateral plasma membrane
GO:0016529 sarcoplasmic reticulum
GO:0019228 neuronal action potential
GO:0030018 Z disc
GO:0030315 T-tubule
GO:0030425 dendrite
GO:0030507 spectrin binding
GO:0030674 protein-macromolecule adaptor activity
GO:0031594 neuromuscular junction
GO:0033268 node of Ranvier
GO:0034112 positive regulation of homotypic cell-cell adhesion
GO:0042383 sarcolemma
GO:0043001 Golgi to plasma membrane protein transport
GO:0043005 neuron projection
GO:0043034 costamere
GO:0043194 axon initial segment
GO:0043266 regulation of potassium ion transport
GO:0044325 transmembrane transporter binding
GO:0045184 establishment of protein localization
GO:0045211 postsynaptic membrane
GO:0045296 cadherin binding
GO:0045838 positive regulation of membrane potential
GO:0071286 cellular response to magnesium ion
GO:0071709 membrane assembly
GO:0072659 protein localization to plasma membrane
GO:0072660 maintenance of protein location in plasma membrane
GO:0090314 positive regulation of protein targeting to membrane
GO:0099612 protein localization to axon
GO:1900827 positive regulation of membrane depolarization during cardiac muscle cell action potential
GO:1902260 negative regulation of delayed rectifier potassium channel activity
GO:2000651 positive regulation of sodium ion transmembrane transporter activity
GO:2001259 positive regulation of cation channel activity

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection
Cytoplasm
Golgi apparatus
Lysosome

Domains

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DomainNameCategoryType
IPR000488 Death domainDomainDomain
IPR000906 ZU5 domainDomainDomain
IPR002110 Ankyrin repeatRepeatRepeat
IPR011029 Death-like domain superfamilyFamilyHomologous superfamily
IPR020683 Ankyrin repeat-containing domainDomainDomain
IPR036770 Ankyrin repeat-containing domain superfamilyFamilyHomologous superfamily
IPR037971 Ankyrin-3, death domainDomainDomain
IPR040745 Ankyrin, UPA domainDomainDomain

Diseases

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Interactions

37 interactions

InteractorPartnerSourcesPublicationsLink
ANK3_HUMANSMAD2_HUMANBioGRID, HPRD, IntAct, MINT15231748 20195357 details
ANK3_HUMANSMAD3_HUMANBioGRID, HPRD, MINT15231748 details
ANK3_HUMANMK06_HUMANBioGRID, IntAct20936779 details
ANK3_HUMANFLNC_HUMANbhf-ucl, BioGRID21223964 details
ANK3_HUMANPLEC_HUMANbhf-ucl, BioGRID21223964 details
ANK3_HUMANNAB2_HUMANBioGRID, IntAct32296183 details
ANK3_HUMANSCN5A_HUMANDIP19805355 details
ANK3_HUMANAP3B1_HUMANDIP19934039 details
ANK3_HUMANSRPK2_HUMANBioGRID26167880 details
ANK3_HUMANGBRAP_HUMANBioGRID29867141 details
ANK3_HUMANMLP3A_HUMANBioGRID29867141 details
ANK3_HUMANMLP3C_HUMANBioGRID29867141 details
ANK3_HUMANUSP9X_HUMANBioGRID32460012 details
ANK3_HUMANHOOK1_HUMANHPRD15823567 details
ANK3_HUMANTNR6_HUMANHPRD14694156 details
ANK3_HUMANNS1BP_HUMANBioGRID, IntAct27173435 unassigned1312 details
ANK3_HUMANTF3C4_HUMANBioGRID, IntAct27173435 unassigned1312 details
ANK3_HUMANEP15R_HUMANBioGRID, IntAct27173435 unassigned1312 details
ANK3_HUMANMCM6_HUMANBioGRID, IntAct27173435 unassigned1312 details
ANK3_HUMANMCM2_HUMANBioGRID, IntAct25963833 27173435 unassigned1312 details
ANK3_HUMANMCM4_HUMANBioGRID, IntAct27173435 unassigned1312 details
ANK3_HUMANJIP4_HUMANBioGRID, IntAct27173435 unassigned1312 details
ANK3_HUMANUBP15_HUMANBioGRID, IntAct27173435 unassigned1312 details
ANK3_HUMANPICAL_HUMANIntAct31413325 details
ANK3_HUMANNDEL1_HUMANIntAct31413325 details
ANK3_HUMANDISC1_HUMANIntAct31413325 details
ANK3_HUMANTNIK_HUMANIntAct31413325 details
ANK3_HUMANKCNC1_HUMANBioGRID, HPRD12805291 details
ANK3_HUMANSPTN4_HUMANBioGRID, HPRD11807096 details
ANK3_HUMANTIAM1_HUMANBioGRID10893266 details
ANK3_HUMANSCN1B_HUMANBioGRID, HPRD11997395 14761957 details
ANK3_HUMANGBRL1_HUMANBioGRID29867141 details
ANK3_HUMANMLP3B_HUMANBioGRID29867141 details
ANK3_HUMANSCN2A_HUMANHPRD12036953 details
ANK3_HUMANP85A_HUMANHPRD16377635 details
ANK3_HUMANSCNNB_HUMANHPRD11997395 details
ANK3_HUMANFADD_HUMANHPRD14694156 details