Entity Details

Primary name GRIK3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13003
EntryNameGRIK3_HUMAN
FullNameGlutamate receptor ionotropic, kainate 3
TaxID9606
Evidenceevidence at transcript level
Length919
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesGRIK3

GO terms

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GOName
GO:0001640 adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
GO:0004970 ionotropic glutamate receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007215 glutamate receptor signaling pathway
GO:0007216 G protein-coupled glutamate receptor signaling pathway
GO:0008066 glutamate receptor activity
GO:0015276 ligand-gated ion channel activity
GO:0015277 kainate selective glutamate receptor activity
GO:0030424 axon
GO:0030425 dendrite
GO:0032839 dendrite cytoplasm
GO:0032983 kainate selective glutamate receptor complex
GO:0035249 synaptic transmission, glutamatergic
GO:0038023 signaling receptor activity
GO:0042391 regulation of membrane potential
GO:0042734 presynaptic membrane
GO:0043195 terminal bouton
GO:0043204 perikaryon
GO:0045211 postsynaptic membrane
GO:0050804 modulation of chemical synaptic transmission
GO:0051967 negative regulation of synaptic transmission, glutamatergic
GO:0098978 glutamatergic synapse
GO:0099507 ligand-gated ion channel activity involved in regulation of presynaptic membrane potential
GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR001320 Ionotropic glutamate receptorDomainDomain
IPR001508 Ionotropic glutamate receptor, metazoaFamilyFamily
IPR001828 Receptor, ligand binding regionDomainDomain
IPR019594 Ionotropic glutamate receptor, L-glutamate and glycine-binding domainDomainDomain
IPR028082 Periplasmic binding protein-like IFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00142 Glutamic acidDrugbanksmall molecule
DB00237 ButabarbitalDrugbanksmall molecule
DB00273 TopiramateDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
GRIK3_HUMANGRIK5_HUMANBioGRID, HPRD9466455 details
GRIK3_HUMANFLNA_HUMANHPRD11943148 details