Entity Details

Primary name ABCC2
Entity type gene
Source Source Link

Details

PrimaryID1244
RefseqGeneNG_011798
SymbolABCC2
NameATP binding cassette subfamily C member 2
Chromosome10
Location10q24.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-12-01
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsMRP2_HUMAN

GO terms

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GOName
GO:0005524 ATP binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006855 drug transmembrane transport
GO:0006954 inflammatory response
GO:0006979 response to oxidative stress
GO:0007565 female pregnancy
GO:0008514 organic anion transmembrane transporter activity
GO:0008559 ABC-type xenobiotic transporter activity
GO:0009408 response to heat
GO:0009986 cell surface
GO:0010629 negative regulation of gene expression
GO:0015127 bilirubin transmembrane transporter activity
GO:0015431 ABC-type glutathione S-conjugate transporter activity
GO:0015694 mercury ion transport
GO:0015721 bile acid and bile salt transport
GO:0015722 canalicular bile acid transport
GO:0015723 bilirubin transport
GO:0015732 prostaglandin transport
GO:0016020 membrane
GO:0016324 apical plasma membrane
GO:0019904 protein domain specific binding
GO:0030644 cellular chloride ion homeostasis
GO:0031427 response to methotrexate
GO:0031526 brush border membrane
GO:0032355 response to estradiol
GO:0033762 response to glucagon
GO:0035690 cellular response to drug
GO:0038183 bile acid signaling pathway
GO:0042167 heme catabolic process
GO:0042178 xenobiotic catabolic process
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0042910 xenobiotic transmembrane transporter activity
GO:0043627 response to estrogen
GO:0046581 intercellular canaliculus
GO:0046618 drug export
GO:0046685 response to arsenic-containing substance
GO:0046691 intracellular canaliculus
GO:0055085 transmembrane transport
GO:0070327 thyroid hormone transport
GO:0070633 transepithelial transport
GO:0071222 cellular response to lipopolysaccharide
GO:0071347 cellular response to interleukin-1
GO:0071354 cellular response to interleukin-6
GO:0071356 cellular response to tumor necrosis factor
GO:0071549 cellular response to dexamethasone stimulus
GO:0071716 leukotriene transport
GO:0097327 response to antineoplastic agent
GO:0120188 regulation of bile acid secretion
GO:0150104 transport across blood-brain barrier
GO:1901086 benzylpenicillin metabolic process
GO:1904486 response to 17alpha-ethynylestradiol
GO:1990961 xenobiotic detoxification by transmembrane export across the plasma membrane
GO:1990962 xenobiotic transport across blood-brain barrier

Diseases

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Interactions

52 interactions

InteractorPartnerSourcesPublicationsLink
ABCC2UBQLN1BioGRID, IntAct21988832 details
ABCC2AZIN1BioGRID, IntAct21988832 details
ABCC2NFKB1BioGRID, IntAct21988832 details
ABCC2MCPH1BioGRID, IntAct21988832 details
ABCC2PDZK1BioGRID, HPRD10496535 12615054 21059598 details
ABCC2SLC9A3R1BioGRID, HPRD12615054 25163515 details
ABCC2PDZD3BioGRID, HPRD12615054 details
ABCC2RDXBioGRID, HPRD12068294 25163515 details
ABCC2HSPA4BioGRID21059598 details
ABCC2TUBB3BioGRID21059598 details
ABCC2AP2M1BioGRID31316180 details
ABCC2CLTCBioGRID31316180 details
ABCC2CANXHPRD12222674 details
ABCC2HNRNPDLBioGRID, IntAct30021884 details
ABCC2NDUFA2BioGRID22939629 details
ABCC2VAMP2BioGRID22939629 details
ABCC2MRPL23BioGRID22939629 details
ABCC2OXA1LBioGRID22939629 details
ABCC2RAB14BioGRID22939629 details
ABCC2TOMM70BioGRID22939629 details
ABCC2MRPL37BioGRID22939629 details
ABCC2MRPL57BioGRID22939629 details
ABCC2NDUFB9BioGRID22939629 details
ABCC2SSR1BioGRID22939629 details
ABCC2TOMM22BioGRID22939629 details
ABCC2ATP6V1B1BioGRID22939629 details
ABCC2ATP6V1E1BioGRID22939629 details
ABCC2MRPL24BioGRID22939629 details
ABCC2RAB11BBioGRID22939629 details
ABCC2MRPS26BioGRID22939629 details
ABCC2EIF4A1BioGRID22939629 details
ABCC2EEF1A1BioGRID22939629 details
ABCC2PTRH2BioGRID22939629 details
ABCC2SLC30A5BioGRID22939629 details
ABCC2JUPBioGRID22939629 details
ABCC2TOMM20BioGRID22939629 details
ABCC2MMGT1BioGRID22939629 details
ABCC2TCIRG1BioGRID22939629 details
ABCC2PRR3BioGRID22939629 details
ABCC2NDUFS8BioGRID22939629 details
ABCC2MRPL10BioGRID22939629 details
ABCC2NDUFA10BioGRID22939629 details
ABCC2CHCHD2BioGRID22939629 details
ABCC2RAB31BioGRID22939629 details
ABCC2NDUFA9BioGRID22939629 details
ABCC2UQCRFS1BioGRID22939629 details
ABCC2MRPS35BioGRID22939629 details
ABCC2PICALMBioGRID22939629 details
ABCC2MRPS28BioGRID22939629 details
ABCC2SYNJ2BPBioGRID22939629 details
ABCC2KRASBioGRID30639242 details
ABCC2PRKD2BioGRID30652415 details