Entity Details

Primary name OLIG2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13516
EntryNameOLIG2_HUMAN
FullNameOligodendrocyte transcription factor 2
TaxID9606
Evidenceevidence at protein level
Length323
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesOLIG2

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0021522 spinal cord motor neuron differentiation
GO:0021530 spinal cord oligodendrocyte cell fate specification
GO:0021794 thalamus development
GO:0030182 neuron differentiation
GO:0042552 myelination
GO:0042802 identical protein binding
GO:0045665 negative regulation of neuron differentiation
GO:0046983 protein dimerization activity
GO:0048663 neuron fate commitment
GO:0048714 positive regulation of oligodendrocyte differentiation
GO:0071837 HMG box domain binding
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR032658 Oligodendrocyte transcription factor 2FamilyFamily
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table