Entity Details

Primary name CYP7A1
Entity type gene
Source Source Link

Details

PrimaryID1581
RefseqGeneNG_007969
SymbolCYP7A1
Namecytochrome P450 family 7 subfamily A member 1
Chromosome8
Location8q12.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1997-07-25
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCP7A1_HUMAN

GO terms

Show/Hide Table
GOName
GO:0005506 iron ion binding
GO:0005789 endoplasmic reticulum membrane
GO:0006699 bile acid biosynthetic process
GO:0006707 cholesterol catabolic process
GO:0008123 cholesterol 7-alpha-monooxygenase activity
GO:0008395 steroid hydroxylase activity
GO:0010468 regulation of gene expression
GO:0015721 bile acid and bile salt transport
GO:0016021 integral component of membrane
GO:0016125 sterol metabolic process
GO:0019222 regulation of metabolic process
GO:0020037 heme binding
GO:0032966 negative regulation of collagen biosynthetic process
GO:0033782 24-hydroxycholesterol 7alpha-hydroxylase activity
GO:0038183 bile acid signaling pathway
GO:0042632 cholesterol homeostasis
GO:0043231 intracellular membrane-bounded organelle
GO:0045471 response to ethanol
GO:0045542 positive regulation of cholesterol biosynthetic process
GO:0045717 negative regulation of fatty acid biosynthetic process
GO:0070857 regulation of bile acid biosynthetic process
GO:0071333 cellular response to glucose stimulus
GO:0071397 cellular response to cholesterol

Diseases

Show/Hide Table

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
CYP7A1NR5A2bhf-ucl15205472 details
CYP7A1HNF4Abhf-ucl16488887 details
CYP7A1PPARGC1Abhf-ucl16488887 details
CYP7A1PROX1bhf-ucl16488887 details