Entity Details

Primary name DRD2
Entity type gene
Source Source Link

Details

PrimaryID1813
RefseqGeneNG_008841
SymbolDRD2
Namedopamine receptor D2
Chromosome11
Location11q23.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-07-27
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsDRD2_HUMAN

GO terms

Show/Hide Table
GOName
GO:0000139 Golgi membrane
GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go
GO:0001659 temperature homeostasis
GO:0001666 response to hypoxia
GO:0001669 acrosomal vesicle
GO:0001933 negative regulation of protein phosphorylation
GO:0001975 response to amphetamine
GO:0001976 nervous system process involved in regulation of systemic arterial blood pressure
GO:0002027 regulation of heart rate
GO:0002028 regulation of sodium ion transport
GO:0002031 G protein-coupled receptor internalization
GO:0002052 positive regulation of neuroblast proliferation
GO:0002092 positive regulation of receptor internalization
GO:0004930 G protein-coupled receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005929 cilium
GO:0006874 cellular calcium ion homeostasis
GO:0006914 autophagy
GO:0007194 negative regulation of adenylate cyclase activity
GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway
GO:0007270 neuron-neuron synaptic transmission
GO:0007409 axonogenesis
GO:0007416 synapse assembly
GO:0007608 sensory perception of smell
GO:0007616 long-term memory
GO:0007625 grooming behavior
GO:0007626 locomotory behavior
GO:0007628 adult walking behavior
GO:0008104 protein localization
GO:0008285 negative regulation of cell population proliferation
GO:0008306 associative learning
GO:0008542 visual learning
GO:0009416 response to light stimulus
GO:0009636 response to toxic substance
GO:0010039 response to iron ion
GO:0014059 regulation of dopamine secretion
GO:0014069 postsynaptic density
GO:0014854 response to inactivity
GO:0015459 potassium channel regulator activity
GO:0016055 Wnt signaling pathway
GO:0016328 lateral plasma membrane
GO:0021756 striatum development
GO:0021769 orbitofrontal cortex development
GO:0021853 cerebral cortex GABAergic interneuron migration
GO:0021984 adenohypophysis development
GO:0030139 endocytic vesicle
GO:0030336 negative regulation of cell migration
GO:0030424 axon
GO:0030425 dendrite
GO:0030432 peristalsis
GO:0030672 synaptic vesicle membrane
GO:0031223 auditory behavior
GO:0032147 activation of protein kinase activity
GO:0032228 regulation of synaptic transmission, GABAergic
GO:0032467 positive regulation of cytokinesis
GO:0032922 circadian regulation of gene expression
GO:0033602 negative regulation of dopamine secretion
GO:0034776 response to histamine
GO:0035094 response to nicotine
GO:0035240 dopamine binding
GO:0035255 ionotropic glutamate receptor binding
GO:0035556 intracellular signal transduction
GO:0035810 positive regulation of urine volume
GO:0035815 positive regulation of renal sodium excretion
GO:0036126 sperm flagellum
GO:0040018 positive regulation of multicellular organism growth
GO:0042220 response to cocaine
GO:0042321 negative regulation of circadian sleep/wake cycle, sleep
GO:0042417 dopamine metabolic process
GO:0042493 response to drug
GO:0042756 drinking behavior
GO:0042802 identical protein binding
GO:0043197 dendritic spine
GO:0043204 perikaryon
GO:0043266 regulation of potassium ion transport
GO:0043278 response to morphine
GO:0043473 pigmentation
GO:0043666 regulation of phosphoprotein phosphatase activity
GO:0043679 axon terminus
GO:0044877 protein-containing complex binding
GO:0045202 synapse
GO:0045745 positive regulation of G protein-coupled receptor signaling pathway
GO:0045776 negative regulation of blood pressure
GO:0045824 negative regulation of innate immune response
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046676 negative regulation of insulin secretion
GO:0046717 acid secretion
GO:0048148 behavioral response to cocaine
GO:0048149 behavioral response to ethanol
GO:0048169 regulation of long-term neuronal synaptic plasticity
GO:0048678 response to axon injury
GO:0048755 branching morphogenesis of a nerve
GO:0050482 arachidonic acid secretion
GO:0050709 negative regulation of protein secretion
GO:0051209 release of sequestered calcium ion into cytosol
GO:0051481 negative regulation of cytosolic calcium ion concentration
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
GO:0051584 regulation of dopamine uptake involved in synaptic transmission
GO:0051586 positive regulation of dopamine uptake involved in synaptic transmission
GO:0051823 regulation of synapse structural plasticity
GO:0051898 negative regulation of protein kinase B signaling
GO:0051967 negative regulation of synaptic transmission, glutamatergic
GO:0060079 excitatory postsynaptic potential
GO:0060124 positive regulation of growth hormone secretion
GO:0060134 prepulse inhibition
GO:0060158 phospholipase C-activating dopamine receptor signaling pathway
GO:0060160 negative regulation of dopamine receptor signaling pathway
GO:0060170 ciliary membrane
GO:0060548 negative regulation of cell death
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway
GO:0090325 regulation of locomotion involved in locomotory behavior
GO:0097730 non-motile cilium
GO:0098691 dopaminergic synapse
GO:0098978 glutamatergic synapse
GO:0098982 GABA-ergic synapse
GO:0099055 integral component of postsynaptic membrane
GO:0099056 integral component of presynaptic membrane
GO:0099170 postsynaptic modulation of chemical synaptic transmission
GO:1900168 positive regulation of glial cell-derived neurotrophic factor production
GO:1900273 positive regulation of long-term synaptic potentiation
GO:1901386 negative regulation of voltage-gated calcium channel activity
GO:1990384 hyaloid vascular plexus regression
GO:2000300 regulation of synaptic vesicle exocytosis

Diseases

Show/Hide Table

Interactions

111 interactions

InteractorPartnerSourcesPublicationsLink
DRD2SLC6A3HPRD, MINT17380124 details
DRD2PPP1R9BBioGRID, HPRD, MINT10391935 17464283 details
DRD2DRD2BioGRID, IntAct, MINT17706924 18668123 21184734 23624386 23637801 28734930 details
DRD2CALM1BioGRID, I2D16051151 19632986 details
DRD2CALM2I2D19632986 details
DRD2CALM3BioGRID, I2D19632986 28298427 details
DRD2ADORA2ABioGRID, HPRD, I2D, IntAct12804599 19632986 23296780 29568380 details
DRD2DRD4IntAct21184734 details
DRD2ARRB2BioGRID, IntAct21256133 25162404 32450252 details
DRD2APH1ABioGRID, MINT28298427 details
DRD2GHITMBioGRID, MINT28298427 details
DRD2RTN3BioGRID, MINT28298427 details
DRD2LPAR1BioGRID, MINT28298427 details
DRD2BCAP29BioGRID, MINT28298427 details
DRD2SYNGR2BioGRID, MINT28298427 details
DRD2TRAM1BioGRID, MINT28298427 details
DRD2YIPF3BioGRID, MINT28298427 details
DRD2CERS1BioGRID, MINT28298427 details
DRD2SLC35B1BioGRID, MINT28298427 details
DRD2ZDHHC4BioGRID, MINT28298427 details
DRD2CCKBRBioGRID, MINT28298427 details
DRD2ARL6IP6BioGRID, MINT28298427 details
DRD2CLDND1BioGRID, MINT28298427 details
DRD2ABCA2BioGRID, MINT28298427 details
DRD2SLC22A17BioGRID, MINT28298427 details
DRD2TTYH1BioGRID, MINT28298427 details
DRD2WLSBioGRID, MINT28298427 details
DRD2GABBR1BioGRID, MINT28298427 details
DRD2SLC4A3BioGRID, MINT28298427 details
DRD2GRINABioGRID, MINT28298427 details
DRD2ATP6V0A2BioGRID, MINT28298427 details
DRD2ARL1BioGRID, MINT28298427 details
DRD2ATP6V0CBioGRID, MINT28298427 details
DRD2BCAP31BioGRID, MINT28298427 details
DRD2ADGRB1BioGRID, MINT28298427 details
DRD2CHPT1BioGRID, MINT28298427 details
DRD2GPR37BioGRID, MINT28298427 details
DRD2CRELD1BioGRID, MINT28298427 details
DRD2SMIM7BioGRID, MINT28298427 details
DRD2ADGRG1BioGRID, MINT28298427 details
DRD2GABBR2BioGRID, MINT28298427 details
DRD2GDPD2BioGRID, MINT28298427 details
DRD2CERS2BioGRID, MINT28298427 details
DRD2NDUFV1BioGRID, MINT28298427 details
DRD2PIGGBioGRID, MINT28298427 details
DRD2PLLPBioGRID, MINT28298427 details
DRD2PLPPR3BioGRID, MINT28298427 details
DRD2PAQR6BioGRID, MINT28298427 details
DRD2RTN1BioGRID, MINT28298427 details
DRD2RTN4BioGRID, MINT28298427 details
DRD2RHBDD2BioGRID, MINT28298427 details
DRD2SPP1BioGRID, MINT28298427 details
DRD2SERINC3BioGRID, MINT28298427 details
DRD2SLC15A4BioGRID, MINT28298427 details
DRD2SLC6A1BioGRID, MINT28298427 details
DRD2TSPAN3BioGRID, MINT28298427 details
DRD2TSPAN7BioGRID, MINT28298427 details
DRD2GPR137BioGRID, MINT28298427 details
DRD2TMEM101BioGRID, MINT28298427 details
DRD2TMEM63ABioGRID, MINT28298427 details
DRD2TFBioGRID, MINT28298427 details
DRD2TMEM11BioGRID, MINT28298427 details
DRD2TMEFF2BioGRID, MINT28298427 details
DRD2WFS1BioGRID, MINT28298427 details
DRD2GNAI1IntAct28734930 details
DRD2GNASIntAct28734930 details
DRD2NTSR1IntAct23624386 details
DRD2HTR2AIntAct20888323 details
DRD2SIGMAR1IntAct23637801 details
DRD2CLIC6BioGRID, HPRD14499480 details
DRD2NCS1BioGRID, HPRD12351722 14709338 21875085 details
DRD2EPB41L1BioGRID, HPRD12181426 details
DRD2FLNABioGRID, HPRD11911837 12181426 details
DRD2PAWRBioGRID16051151 details
DRD2GNB5BioGRID25162404 details
DRD2NEFMBioGRID12122054 details
DRD2SSTR2BioGRID17706924 details
DRD2TRPC1BioGRID18261457 details
DRD2TRPC4BioGRID18261457 details
DRD2TRPC5BioGRID18261457 details
DRD2OPRM1BioGRID31416253 details
DRD2HRH3BioGRID18547596 details
DRD2KBTBD7BioGRID32572597 details
DRD2KBTBD6BioGRID32572597 details
DRD2GIPC1HPRD14617818 details
DRD2CADPS2HPRD15857609 details
DRD2OXTRIntAct22824810 details
DRD2KCNJ3BioGRID12297500 details
DRD2KCNJ6BioGRID, HPRD12297500 details
DRD2KCNJ5BioGRID12297500 details
DRD2PRKCBBioGRID29054428 details
DRD2DNM1BioGRID14709338 details
DRD2DNM2BioGRID14709338 details
DRD2MDM2BioGRID32828283 details
DRD2CADPSHPRD15857609 details
DRD2GRIA2HPRD15858065 details
DRD2NSFHPRD15858065 details
DRD2EPB41HPRD12181426 details
DRD2GNAZHPRD9166747 details
DRD2GNAI2HPRD10978845 details
DRD2GNAI3HPRD10978845 details
DRD2SSTR5HPRD10753124 details
DRD2KCNJ9HPRD12297500 details
DRD2WDR45BioGRID, IntAct28514442 details
DRD2MSRABioGRID, IntAct28514442 details
DRD2NDFIP1BioGRID, IntAct28514442 details
DRD2COLEC12BioGRID, IntAct28514442 details
DRD2VDAC2BioGRID, IntAct30021884 details
DRD2CNR1IntAct28734930 details
DRD2GNB1DIP32528175 details
DRD2EGFRBioGRID28065597 details