Entity Details

Primary name F2R
Entity type gene
Source Source Link

Details

PrimaryID2149
RefseqGeneNG_032906
SymbolF2R
Namecoagulation factor II thrombin receptor
Chromosome5
Location5q13.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-13
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsPAR1_HUMAN

GO terms

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GOName
GO:0000186 obsolete activation of MAPKK activity
GO:0001965 G-protein alpha-subunit binding
GO:0002248 connective tissue replacement involved in inflammatory response wound healing
GO:0003105 negative regulation of glomerular filtration
GO:0004930 G protein-coupled receptor activity
GO:0005102 signaling receptor binding
GO:0005576 extracellular region
GO:0005769 early endosome
GO:0005770 late endosome
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005901 caveola
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006954 inflammatory response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway
GO:0007529 establishment of synaptic specificity at neuromuscular junction
GO:0007596 blood coagulation
GO:0008284 positive regulation of cell population proliferation
GO:0008285 negative regulation of cell population proliferation
GO:0009611 response to wounding
GO:0009653 anatomical structure morphogenesis
GO:0009986 cell surface
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0015057 thrombin-activated receptor activity
GO:0030168 platelet activation
GO:0030193 regulation of blood coagulation
GO:0030194 positive regulation of blood coagulation
GO:0030335 positive regulation of cell migration
GO:0031094 platelet dense tubular network
GO:0031594 neuromuscular junction
GO:0031681 G-protein beta-subunit binding
GO:0032496 response to lipopolysaccharide
GO:0032651 regulation of interleukin-1 beta production
GO:0032755 positive regulation of interleukin-6 production
GO:0032757 positive regulation of interleukin-8 production
GO:0032967 positive regulation of collagen biosynthetic process
GO:0035025 positive regulation of Rho protein signal transduction
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043410 positive regulation of MAPK cascade
GO:0043524 negative regulation of neuron apoptotic process
GO:0043547 positive regulation of GTPase activity
GO:0045211 postsynaptic membrane
GO:0045217 cell-cell junction maintenance
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045907 positive regulation of vasoconstriction
GO:0045987 positive regulation of smooth muscle contraction
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT
GO:0048873 homeostasis of number of cells within a tissue
GO:0051209 release of sequestered calcium ion into cytosol
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
GO:0051928 positive regulation of calcium ion transport
GO:0051930 regulation of sensory perception of pain
GO:0060155 platelet dense granule organization
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0099553 trans-synaptic signaling by endocannabinoid, modulating synaptic transmission
GO:1900134 negative regulation of renin secretion into blood stream

Diseases

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