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Entity Details
Primary name
FGD2
Entity type
gene
Source
Source Link
Details
PrimaryID
221472
RefseqGene
NG_051804
Symbol
FGD2
Name
FYVE, RhoGEF and PH domain containing 2
Chromosome
6
Location
6p21.2
TaxID
9606
Status
live
SourceGenome
genomic
SourceOrigin
natural
CreationDate
2002-05-05
ModificationDate
2021-06-11
Ontological Relatives
UniProt IDs
FGD2_HUMAN
GO terms
Show/Hide Table
GO
Name
GO:0001726
ruffle
GO:0005085
guanyl-nucleotide exchange factor activity
GO:0005634
nucleus
GO:0005737
cytoplasm
GO:0005794
Golgi apparatus
GO:0005829
cytosol
GO:0005856
cytoskeleton
GO:0007010
cytoskeleton organization
GO:0007186
G protein-coupled receptor signaling pathway
GO:0008360
regulation of cell shape
GO:0030027
lamellipodium
GO:0030036
actin cytoskeleton organization
GO:0031267
small GTPase binding
GO:0031901
early endosome membrane
GO:0032587
ruffle membrane
GO:0043065
positive regulation of apoptotic process
GO:0043087
regulation of GTPase activity
GO:0043507
positive regulation of JUN kinase activity
GO:0046847
filopodium assembly
GO:0046872
metal ion binding
GO:0051056
regulation of small GTPase mediated signal transduction
GO:1901981
phosphatidylinositol phosphate binding
Diseases
Show/Hide Table
Interactions
24 interactions
Interactor
Partner
Sources
Publications
Link
FGD2
KLHL12
BioGRID, IntAct
25416956
details
FGD2
TMEM239
BioGRID, IntAct
25416956
details
FGD2
RPRM
BioGRID, IntAct
32296183
details
FGD2
PLEKHG4
BioGRID, IntAct
32296183
details
FGD2
CDC42
BioGRID
32203420
details
FGD2
RNPS1
IntAct
17353931
details
FGD2
ARHGAP18
BioGRID, IntAct
32203420
details
FGD2
TCERG1
BioGRID, IntAct
32203420
details
FGD2
PKP2
BioGRID, IntAct
32203420
details
FGD2
MRPS35
IntAct
32203420
details
FGD2
TMEM263
BioGRID, IntAct
32203420
details
FGD2
UBC
BioGRID
16196087
details
FGD2
MRPS28
BioGRID
32203420
details
FGD2
CAND1
BioGRID
32203420
details
FGD2
CSTA
BioGRID
32203420
details
FGD2
HMGN1
BioGRID
32203420
details
FGD2
HMGN3
BioGRID
32203420
details
FGD2
HMGN5
BioGRID
32203420
details
FGD2
HP1BP3
BioGRID
32203420
details
FGD2
MCM6
BioGRID
32203420
details
FGD2
PIK3R1
BioGRID
32203420
details
FGD2
RBM15
BioGRID
32203420
details
FGD2
RPS27L
BioGRID
32203420
details
FGD2
SDF2L1
BioGRID
32203420
details
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