Entity Details

Primary name CFAP65
Entity type gene
Source Source Link

Details

PrimaryID255101
RefseqGeneNG_051336
SymbolCFAP65
Namecilia and flagella associated protein 65
Chromosome2
Location2q35
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2002-07-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCFA65_HUMAN

GO terms

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GOName
GO:0001669 acrosomal vesicle
GO:0002080 acrosomal membrane
GO:0003723 RNA binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0007288 sperm axoneme assembly
GO:0016021 integral component of membrane
GO:0030317 flagellated sperm motility
GO:0036126 sperm flagellum
GO:0097225 sperm midpiece

Diseases

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Disease IDSourceNameDescription
618664 OMIMSpermatogenic failure 40 (SPGF40)An autosomal recessive infertility disorder characterized by severely reduced or absent sperm motility, due to multiple morphologic anomalies such as absent, short, bent, coiled and irregular-caliber tails. Patient spermatozoa may also show morphologic defects of the sperm head. The disease is caused by variants affecting the gene represented in this entry.

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
CFAP65CCNDBP1BioGRID, IntAct25416956 details
CFAP65LRRK2IntAct31046837 details
CFAP65PRKAR1ABioGRID, IntAct31980649 details
CFAP65GARTBioGRID26344197 details