Entity Details

Primary name SEM3A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14563
EntryNameSEM3A_HUMAN
FullNameSemaphorin-3A
TaxID9606
Evidenceevidence at protein level
Length771
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesSEMA3A

GO terms

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GOName
GO:0001755 neural crest cell migration
GO:0001764 neuron migration
GO:0002027 regulation of heart rate
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005887 integral component of plasma membrane
GO:0006915 apoptotic process
GO:0007411 axon guidance
GO:0007413 axonal fasciculation
GO:0008045 motor neuron axon guidance
GO:0010633 negative regulation of epithelial cell migration
GO:0010977 negative regulation of neuron projection development
GO:0021612 facial nerve structural organization
GO:0021637 trigeminal nerve structural organization
GO:0021675 nerve development
GO:0021772 olfactory bulb development
GO:0021785 branchiomotor neuron axon guidance
GO:0021828 gonadotrophin-releasing hormone neuronal migration to the hypothalamus
GO:0030215 semaphorin receptor binding
GO:0030335 positive regulation of cell migration
GO:0030424 axon
GO:0030425 dendrite
GO:0036486 ventral trunk neural crest cell migration
GO:0038191 neuropilin binding
GO:0045499 chemorepellent activity
GO:0046330 positive regulation of JNK cascade
GO:0048485 sympathetic nervous system development
GO:0048841 regulation of axon extension involved in axon guidance
GO:0048843 negative regulation of axon extension involved in axon guidance
GO:0048846 axon extension involved in axon guidance
GO:0048880 sensory system development
GO:0050919 negative chemotaxis
GO:0060385 axonogenesis involved in innervation
GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching
GO:0061549 sympathetic ganglion development
GO:0061551 trigeminal ganglion development
GO:0071526 semaphorin-plexin signaling pathway
GO:0097490 sympathetic neuron projection extension
GO:0097491 sympathetic neuron projection guidance
GO:0150020 basal dendrite arborization
GO:1901166 neural crest cell migration involved in autonomic nervous system development
GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance
GO:1902287 semaphorin-plexin signaling pathway involved in axon guidance
GO:1903045 neural crest cell migration involved in sympathetic nervous system development
GO:1903375 facioacoustic ganglion development
GO:2000020 positive regulation of male gonad development
GO:2001224 positive regulation of neuron migration

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001627 Sema domainDomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR016201 PSI domainDomainDomain
IPR027231 SemaphorinFamilyFamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR036352 Sema domain superfamilyFamilyHomologous superfamily
IPR042820 Semaphorin-3A, sema domainDomainDomain

Diseases

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Interactions

3 interactions