Entity Details

Primary name DMC1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14565
EntryNameDMC1_HUMAN
FullNameMeiotic recombination protein DMC1/LIM15 homolog
TaxID9606
Evidenceevidence at protein level
Length340
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesDMC1

GO terms

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GOName
GO:0000150 DNA strand exchange activity
GO:0000730 DNA recombinase assembly
GO:0000781 chromosome, telomeric region
GO:0000794 condensed nuclear chromosome
GO:0001541 ovarian follicle development
GO:0001556 oocyte maturation
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003697 single-stranded DNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005694 chromosome
GO:0006312 mitotic recombination
GO:0007129 homologous chromosome pairing at meiosis
GO:0007131 reciprocal meiotic recombination
GO:0007141 male meiosis I
GO:0007283 spermatogenesis
GO:0007286 spermatid development
GO:0007292 female gamete generation
GO:0008094 ATPase, acting on DNA
GO:0042148 strand invasion
GO:0042802 identical protein binding
GO:0051321 meiotic cell cycle
GO:0070192 chromosome organization involved in meiotic cell cycle

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR003593 AAA+ ATPase domainDomainDomain
IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helicalFamilyHomologous superfamily
IPR011940 Meiotic recombination protein Dmc1FamilyFamily
IPR013632 DNA recombination and repair protein Rad51-like, C-terminalDomainDomain
IPR016467 DNA recombination and repair protein, RecA-likeFamilyFamily
IPR020587 DNA recombination and repair protein RecA, monomer-monomer interfaceDomainDomain
IPR020588 DNA recombination and repair protein RecA-like, ATP-binding domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR033925 Rad51/DMC1/RadADomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB03366 ImidazoleDrugbanksmall molecule