Entity Details

Primary name GDNF
Entity type gene
Source Source Link

Details

PrimaryID2668
RefseqGeneNG_011675
SymbolGDNF
Nameglial cell derived neurotrophic factor
Chromosome5
Location5p13.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1995-09-18
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsGDNF_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0001656 metanephros development
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0001755 neural crest cell migration
GO:0001759 organ induction
GO:0001941 postsynaptic membrane organization
GO:0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0005102 signaling receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005794 Golgi apparatus
GO:0007165 signal transduction
GO:0007399 nervous system development
GO:0007411 axon guidance
GO:0007422 peripheral nervous system development
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0008344 adult locomotory behavior
GO:0010468 regulation of gene expression
GO:0021516 dorsal spinal cord development
GO:0021784 postganglionic parasympathetic fiber development
GO:0030116 glial cell-derived neurotrophic factor receptor binding
GO:0030432 peristalsis
GO:0030971 receptor tyrosine kinase binding
GO:0031175 neuron projection development
GO:0032770 positive regulation of monooxygenase activity
GO:0033603 positive regulation of dopamine secretion
GO:0042803 protein homodimerization activity
GO:0043066 negative regulation of apoptotic process
GO:0043524 negative regulation of neuron apoptotic process
GO:0045597 positive regulation of cell differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048255 mRNA stabilization
GO:0048484 enteric nervous system development
GO:0048485 sympathetic nervous system development
GO:0048568 embryonic organ development
GO:0051584 regulation of dopamine uptake involved in synaptic transmission
GO:0060676 ureteric bud formation
GO:0060688 regulation of morphogenesis of a branching structure
GO:0071679 commissural neuron axon guidance
GO:0072107 positive regulation of ureteric bud formation
GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis
GO:1902379 chemoattractant activity involved in axon guidance
GO:2000736 regulation of stem cell differentiation
GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
GO:2001260 regulation of semaphorin-plexin signaling pathway

Diseases

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