Entity Details

Primary name APEX2
Entity type gene
Source Source Link

Details

PrimaryID27301
RefseqGeneNG_012568
SymbolAPEX2
Nameapurinic/apyrimidinic endodeoxyribonuclease 2
ChromosomeX
LocationXp11.21
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-01-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsAPEX2_HUMAN

GO terms

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GOName
GO:0001650 fibrillar center
GO:0003677 DNA binding
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0004519 endonuclease activity
GO:0004528 phosphodiesterase I activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0006284 base-excision repair
GO:0006310 DNA recombination
GO:0007049 cell cycle
GO:0008270 zinc ion binding
GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity
GO:0043231 intracellular membrane-bounded organelle

Diseases

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Interactions

31 interactions

InteractorPartnerSourcesPublicationsLink
APEX2TRIM37BioGRID, HPRD, IntAct16189514 details
APEX2TRAF2BioGRID, HPRD, IntAct16189514 details
APEX2HOOK2BioGRID, HPRD, IntAct16189514 details
APEX2EFEMP2BioGRID, HPRD, IntAct16189514 details
APEX2NINLBioGRID, HPRD, IntAct16189514 details
APEX2CCDC85BBioGRID, HPRD, IntAct16189514 details
APEX2CALCOCO2BioGRID, HPRD, IntAct16189514 details
APEX2TSHZ3BioGRID, IntAct32296183 details
APEX2MKRN3BioGRID, IntAct32296183 details
APEX2LRRK2BioGRID, IntAct29513927 details
APEX2DAPK1BioGRID, IntAct29513927 details
APEX2MFHAS1BioGRID, IntAct29513927 details
APEX2PCNABioGRID, HPRD, UniProt11376153 26030842 details
APEX2NEDD4LBioGRID19953087 details
APEX2APPBioGRID21832049 details
APEX2MAP3K1BioGRID25260751 details
APEX2PGRHPRD12650714 details
APEX2APBA2BioGRID, IntAct28514442 31413325 details
APEX2PEDS1-UBE2V1IntAct25260751 details
APEX2UBE2V1IntAct25260751 details
APEX2UBA1IntAct25260751 details
APEX2UBE2NIntAct25260751 details
APEX2WDR54BioGRID, IntAct28514442 details
APEX2SIRT1BioGRID, IntAct28514442 details
APEX2DDB2BioGRID, IntAct28514442 details
APEX2CUL9BioGRID, IntAct28514442 31343991 details
APEX2CTU2BioGRID, IntAct28514442 details
APEX2CUL7BioGRID, IntAct28514442 details
APEX2RETNBioGRID, IntAct28514442 details
APEX2ERLIN1BioGRID, IntAct30021884 details
APEX2PDE12BioGRID22939629 details