Entity Details

Primary name MR1
Entity type gene
Source Source Link

Details

PrimaryID3140
RefseqGeneNG_042221
SymbolMR1
Namemajor histocompatibility complex, class I-related
Chromosome1
Location1q25.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-19
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsHMR1_HUMAN

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
GO:0002854 positive regulation of T cell mediated cytotoxicity directed against tumor cell target
GO:0005615 extracellular space
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0006955 immune response
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
GO:0019884 antigen processing and presentation of exogenous antigen
GO:0030881 beta-2-microglobulin binding
GO:0031901 early endosome membrane
GO:0031902 late endosome membrane
GO:0032393 MHC class I receptor activity
GO:0033077 T cell differentiation in thymus
GO:0042608 T cell receptor binding
GO:0042612 MHC class I protein complex
GO:0045087 innate immune response
GO:0050829 defense response to Gram-negative bacterium
GO:0050830 defense response to Gram-positive bacterium

Diseases

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Interactions

23 interactions

InteractorPartnerSourcesPublicationsLink
MR1FATE1BioGRID, IntAct25416956 32296183 details
MR1ERMP1BioGRID, IntAct32296183 details
MR1NINJ2BioGRID, IntAct32296183 details
MR1CDS2BioGRID, IntAct32296183 details
MR1GALNT15BioGRID, IntAct32296183 details
MR1EMP3BioGRID, IntAct32296183 details
MR1CXCL9BioGRID, IntAct32296183 details
MR1B2MDIP23051753 details
MR1HLA-EBioGRID, IntAct26186194 28514442 details
MR1TMPRSS11BBioGRID, IntAct28514442 details
MR1TMEM30ABioGRID, IntAct26186194 28514442 details
MR1ST8SIA4BioGRID, IntAct28514442 details
MR1IL17RCBioGRID, IntAct28514442 details
MR1MPPE1BioGRID, IntAct28514442 details
MR1ZACNBioGRID, IntAct26186194 28514442 details
MR1TCTN2BioGRID, IntAct28514442 details
MR1CD1BBioGRID26186194 details
MR1ITM2BBioGRID26186194 details
MR1HLA-CBioGRID26186194 details
MR1BTNL8BioGRID26186194 details
MR1SIAEBioGRID26186194 details
MR1PON2BioGRID26186194 details
MR1DDX58BioGRID32513696 details