Entity Details

Primary name MECP2
Entity type gene
Source Source Link

Details

PrimaryID4204
RefseqGeneNG_007107
SymbolMECP2
Namemethyl-CpG binding protein 2
ChromosomeX
LocationXq28
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-09-20
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsMECP2_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000792 heterochromatin
GO:0001662 behavioral fear response
GO:0001666 response to hypoxia
GO:0001964 startle response
GO:0001976 nervous system process involved in regulation of systemic arterial blood pressure
GO:0002087 regulation of respiratory gaseous exchange by nervous system process
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0003714 transcription corepressor activity
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0006020 inositol metabolic process
GO:0006342 chromatin silencing
GO:0006349 regulation of gene expression by genetic imprinting
GO:0006541 glutamine metabolic process
GO:0006576 cellular biogenic amine metabolic process
GO:0007052 mitotic spindle organization
GO:0007416 synapse assembly
GO:0007585 respiratory gaseous exchange by respiratory system
GO:0007616 long-term memory
GO:0008104 protein localization
GO:0008134 transcription factor binding
GO:0008211 glucocorticoid metabolic process
GO:0008284 positive regulation of cell population proliferation
GO:0008327 methyl-CpG binding
GO:0008344 adult locomotory behavior
GO:0008542 visual learning
GO:0009791 post-embryonic development
GO:0010385 double-stranded methylated DNA binding
GO:0010629 negative regulation of gene expression
GO:0010971 positive regulation of G2/M transition of mitotic cell cycle
GO:0016358 dendrite development
GO:0016525 negative regulation of angiogenesis
GO:0016571 histone methylation
GO:0016573 histone acetylation
GO:0019230 proprioception
GO:0019233 sensory perception of pain
GO:0019904 protein domain specific binding
GO:0021549 cerebellum development
GO:0021591 ventricular system development
GO:0032048 cardiolipin metabolic process
GO:0035176 social behavior
GO:0035197 siRNA binding
GO:0042551 neuron maturation
GO:0043524 negative regulation of neuron apoptotic process
GO:0043537 negative regulation of blood vessel endothelial cell migration
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046470 phosphatidylcholine metabolic process
GO:0047485 protein N-terminus binding
GO:0051151 negative regulation of smooth muscle cell differentiation
GO:0051707 response to other organism
GO:0060079 excitatory postsynaptic potential
GO:0060260 regulation of transcription initiation from RNA polymerase II promoter
GO:0060291 long-term synaptic potentiation
GO:0090063 positive regulation of microtubule nucleation
GO:0098794 postsynapse
GO:1900114 positive regulation of histone H3-K9 trimethylation
GO:1905643 positive regulation of DNA methylation
GO:1990841 promoter-specific chromatin binding
GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation

Diseases

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Interactions

273 interactions

InteractorPartnerSourcesPublicationsLink
MECP2SMARCA2BioGRID, HPRD, IntAct15696166 20093853 details
MECP2HIPK2BioGRID, MINT19820693 details
MECP2SOX18BioGRID, IntAct21988832 details
MECP2TBL1XR1BioGRID, DIP23770565 28348241 details
MECP2SIN3ABioGRID, DIP, HPRD10773092 11441023 14593184 15322089 22615490 23770565 9620779 9620804 details
MECP2HSPB1IntAct32814053 details
MECP2AP2B1IntAct32814053 details
MECP2RASSF5IntAct32814053 details
MECP2ABHD17CIntAct32814053 details
MECP2OTUD7BIntAct32814053 details
MECP2OTUB1IntAct32814053 details
MECP2GPR75-ASB3IntAct32814053 details
MECP2ASB3IntAct32814053 details
MECP2KLHL20IntAct32814053 details
MECP2RAB38IntAct32814053 details
MECP2CYFIP1IntAct32814053 details
MECP2DDX20IntAct32814053 details
MECP2RASSF1IntAct32814053 details
MECP2KAT5IntAct32814053 details
MECP2IQSEC1IntAct32814053 details
MECP2STX11IntAct32814053 details
MECP2PIAS1IntAct32814053 details
MECP2COPS3IntAct32814053 details
MECP2RNF112IntAct32814053 details
MECP2BRK1IntAct32814053 details
MECP2TXNIntAct32814053 details
MECP2SMN1IntAct32814053 details
MECP2SMN2IntAct32814053 details
MECP2SMARCB1BioGRID, HPRD, IntAct1569166 15696166 32814053 details
MECP2NAP1L3IntAct32814053 details
MECP2MSH5IntAct32814053 details
MECP2LYNIntAct32814053 details
MECP2EYA3IntAct32814053 details
MECP2CTNNB1IntAct32814053 details
MECP2TRIM74IntAct32814053 details
MECP2SPATA12IntAct32814053 details
MECP2KRTAP8-1IntAct32814053 details
MECP2FOXR1IntAct32814053 details
MECP2TRIM69IntAct32814053 details
MECP2RNF183IntAct32814053 details
MECP2ATP5IF1IntAct32814053 details
MECP2MGARPIntAct32814053 details
MECP2NEFLIntAct32814053 details
MECP2PRPS1IntAct32814053 details
MECP2WFS1IntAct32814053 details
MECP2OPTNIntAct32814053 details
MECP2HTTIntAct32814053 details
MECP2PRPF40ABioGRID, HPRD14618241 9171351 details
MECP2HMGB1BioGRID, HPRD11748221 details
MECP2SKIBioGRID, HPRD11441023 details
MECP2NCOR1BioGRID, HPRD11441023 28348241 details
MECP2GTF2BBioGRID10756192 details
MECP2H3C15BioGRID12427740 details
MECP2DNMT1BioGRID12473678 details
MECP2HDAC1BioGRID12473678 14593184 14647463 16331260 details
MECP2PRPF40BBioGRID14618241 details
MECP2SPI1BioGRID14647463 16331260 details
MECP2LBRBioGRID19331822 details
MECP2CDKL5BioGRID15917271 details
MECP2YY1BioGRID20504995 24981860 details
MECP2RNF4BioGRID25355316 29180619 details
MECP2DNMT3LBioGRID24952347 details
MECP2TBL1XBioGRID28348241 details
MECP2ATRXDIP17296936 details
MECP2RBPJBioGRID, MINT16763620 25609649 details
MECP2RCOR1BioGRID12399542 details
MECP2SUV39H1BioGRID12399542 details
MECP2SP1BioGRID15109260 20385708 details
MECP2SMARCE1BioGRID15696166 details
MECP2CBX5BioGRID17698499 22615490 details
MECP2YBX1BioGRID16251272 22615490 details
MECP2SP3BioGRID20385708 details
MECP2SOX2BioGRID20368621 details
MECP2TERF2BioGRID20811636 details
MECP2SMC3BioGRID22615490 details
MECP2CBX1BioGRID22615490 details
MECP2CBX3BioGRID22615490 34079125 details
MECP2H2AC20BioGRID21278419 details
MECP2H2BC21BioGRID21278419 details
MECP2H3C14BioGRID21278419 details
MECP2H4C6BioGRID21278419 details
MECP2AIM2BioGRID, IntAct25665578 details
MECP2PYHIN1BioGRID, IntAct25665578 details
MECP2MACROH2A1BioGRID, IntAct25417162 details
MECP2MAXBioGRID, MINT25609649 details
MECP2CREB1BioGRID, MINT25609649 details
MECP2FOXC1BioGRID, MINT25609649 details
MECP2FOXE1BioGRID, MINT25609649 details
MECP2FOXI2BioGRID, MINT25609649 details
MECP2TEAD2BioGRID, MINT25609649 details
MECP2JUNMINT25609649 details
MECP2CDC42BioGRID, IntAct26496610 details
MECP2PLK1BioGRID, IntAct26496610 details
MECP2EXOSC4BioGRID, IntAct26496610 details
MECP2AP4S1BioGRID, IntAct26496610 details
MECP2CHMP4BBioGRID, IntAct26496610 details
MECP2BLMBioGRID, IntAct28514442 details
MECP2RRP7ABioGRID, IntAct28514442 details
MECP2MYBBP1ABioGRID, IntAct28514442 details
MECP2RPL36BioGRID, IntAct28514442 details
MECP2NOC2LBioGRID, IntAct28514442 details
MECP2NOP16BioGRID, IntAct28514442 details
MECP2FCF1BioGRID, IntAct28514442 details
MECP2RPL26L1BioGRID, IntAct28514442 details
MECP2RBAKBioGRID, IntAct28514442 details
MECP2DDX56BioGRID, IntAct24981860 28514442 details
MECP2TEX10BioGRID, IntAct28514442 details
MECP2RBM28BioGRID, IntAct28514442 details
MECP2NLE1BioGRID, IntAct28514442 details
MECP2SDAD1BioGRID, IntAct28514442 details
MECP2BAZ1ABioGRID, IntAct28514442 details
MECP2DDX21BioGRID, IntAct28514442 details
MECP2ZCCHC17BioGRID, IntAct28514442 details
MECP2CHMP1ABioGRID, IntAct28514442 details
MECP2DDX31BioGRID, IntAct28514442 details
MECP2RPF2BioGRID, IntAct28514442 details
MECP2NOL6BioGRID, IntAct28514442 details
MECP2TAF1DBioGRID, IntAct28514442 details
MECP2ESF1BioGRID, IntAct28514442 details
MECP2NAT10BioGRID, IntAct28514442 details
MECP2DDX24BioGRID, IntAct28514442 details
MECP2GTPBP4BioGRID, IntAct28514442 details
MECP2SRSF8BioGRID, IntAct28514442 details
MECP2TWNKBioGRID, IntAct28514442 details
MECP2LENG8BioGRID, IntAct28514442 details
MECP2NSD1BioGRID, IntAct28514442 details
MECP2DGCR8BioGRID, IntAct28514442 details
MECP2BBXBioGRID, IntAct28514442 details
MECP2TFB1MBioGRID, IntAct28514442 details
MECP2ZNF483BioGRID, IntAct28514442 details
MECP2BRIX1BioGRID, IntAct28514442 details
MECP2DDX54BioGRID, IntAct28514442 details
MECP2WDR36BioGRID, IntAct28514442 details
MECP2DDX51BioGRID, IntAct28514442 details
MECP2SRBD1BioGRID, IntAct28514442 details
MECP2RIOX2BioGRID, IntAct28514442 details
MECP2CENPVBioGRID, IntAct28514442 details
MECP2TRMT1LBioGRID, IntAct28514442 details
MECP2NOL8BioGRID, IntAct28514442 details
MECP2NKAPD1BioGRID, IntAct28514442 details
MECP2NEPROBioGRID, IntAct28514442 details
MECP2SPOUT1BioGRID, IntAct28514442 details
MECP2TAF1BBioGRID, IntAct28514442 details
MECP2C18orf21BioGRID, IntAct28514442 details
MECP2ZNF800BioGRID, IntAct28514442 details
MECP2TAF1ABioGRID, IntAct28514442 details
MECP2TAF1CBioGRID, IntAct28514442 details
MECP2PWP2BioGRID, IntAct28514442 details
MECP2PDCD11BioGRID, IntAct28514442 details
MECP2RRP1BBioGRID, IntAct28514442 details
MECP2TRIP12BioGRID, IntAct28514442 details
MECP2URB2BioGRID, IntAct28514442 details
MECP2GNL2BioGRID, IntAct28514442 details
MECP2TOP3ABioGRID, IntAct28514442 details
MECP2ITGB3BPBioGRID, IntAct28514442 details
MECP2RPL18BioGRID, IntAct28514442 details
MECP2CEBPZBioGRID, IntAct28514442 details
MECP2RPL8BioGRID, IntAct28514442 details
MECP2RPL32BioGRID, IntAct28514442 details
MECP2RPL10ABioGRID, IntAct28514442 details
MECP2RPL7ABioGRID, IntAct28514442 details
MECP2RPS8BioGRID, IntAct28514442 details
MECP2RPL27BioGRID, IntAct28514442 details
MECP2RPL15BioGRID, IntAct28514442 details
MECP2HIRABioGRID, IntAct28514442 details
MECP2FXR2BioGRID, IntAct28514442 details
MECP2METAP2BioGRID, IntAct28514442 details
MECP2RPL29BioGRID, IntAct28514442 details
MECP2RPL5BioGRID, IntAct28514442 details
MECP2NOP2BioGRID, IntAct28514442 details
MECP2MKI67BioGRID, IntAct26949251 28514442 details
MECP2RPL3BioGRID, IntAct28514442 details
MECP2RPL12BioGRID, IntAct28514442 details
MECP2RPL13BioGRID, IntAct28514442 details
MECP2H1-6BioGRID, IntAct28514442 details
MECP2EIF2AK2BioGRID, IntAct28514442 details
MECP2RPL17BioGRID, IntAct28514442 details
MECP2RPLP2BioGRID, IntAct28514442 details
MECP2RPP40BioGRID, IntAct28514442 details
MECP2ZNF354ABioGRID, IntAct28514442 details
MECP2URB1BioGRID, IntAct28514442 details
MECP2RRP8BioGRID, IntAct28514442 details
MECP2NVLBioGRID, IntAct28514442 details
MECP2KPNA4BioGRID, IntAct, MINT24981860 28514442 details
MECP2KPNA3BioGRID, IntAct, MINT24981860 28514442 details
MECP2ZNF593BioGRID, IntAct28514442 details
MECP2H2BC18BioGRID, IntAct28514442 details
MECP2GTPBP10BioGRID, IntAct28514442 details
MECP2HDAC3DIP23770565 details
MECP2H2BC5MINT25281560 details
MECP2H2BC8BioGRID, MINT25281560 34079125 details
MECP2H2BC7MINT25281560 details
MECP2H2BC6MINT25281560 details
MECP2H2BC10MINT25281560 details
MECP2H2BC4MINT25281560 details
MECP2H3C1BioGRID, MINT25281560 30102379 34079125 details
MECP2H3C4MINT25281560 30102379 details
MECP2H3C3MINT25281560 30102379 details
MECP2H3C6MINT25281560 30102379 details
MECP2H3C11MINT25281560 30102379 details
MECP2H3C8MINT25281560 30102379 details
MECP2H3C12MINT25281560 30102379 details
MECP2H3C10MINT25281560 30102379 details
MECP2H3C2MINT25281560 30102379 details
MECP2H3C7MINT25281560 30102379 details
MECP2ESR1BioGRID, IntAct31527615 details
MECP2ARHGAP22BioGRID, IntAct32203420 details
MECP2FGD1BioGRID, IntAct32203420 details
MECP2CCNT1BioGRID, MINT24981860 details
MECP2HEXIM1BioGRID, MINT24981860 details
MECP2PPIEBioGRID, MINT24981860 details
MECP2REC8BioGRID, MINT24981860 details
MECP2SP100BioGRID, MINT24981860 details
MECP2XPCBioGRID22939629 details
MECP2CATBioGRID22939629 details
MECP2HPDLBioGRID22939629 details
MECP2HECW2BioGRID24163370 details
MECP2NKX2-1BioGRID28192407 details
MECP2EZH2BioGRID27634302 details
MECP2XRCC6BioGRID30585729 details
MECP2H4C1BioGRID30804502 details
MECP2NSD2BioGRID31248990 details
MECP2PRC1BioGRID31586073 details
MECP2BRD3BioGRID31753913 details
MECP2ARHGAP23BioGRID32203420 details
MECP2ARHGEF16BioGRID32203420 details
MECP2ARHGEF19BioGRID32203420 details
MECP2ARHGEF5BioGRID32203420 details
MECP2ZNF263BioGRID32051553 details
MECP2BRD4BioGRID31239290 details
MECP2CPSF7BioGRID24981860 details
MECP2LRPAP1BioGRID24981860 details
MECP2DDX42BioGRID24981860 details
MECP2CTTNBioGRID24981860 details
MECP2MEPCEBioGRID24981860 details
MECP2XAB2BioGRID24981860 details
MECP2PIP4K2ABioGRID24981860 details
MECP2ISY1BioGRID24981860 details
MECP2PPIL4BioGRID24981860 details
MECP2PPP1R10BioGRID24981860 details
MECP2NSRP1BioGRID24981860 details
MECP2POP1BioGRID24981860 details
MECP2NUFIP2BioGRID24981860 details
MECP2TOP1BioGRID24981860 details
MECP2PSPC1BioGRID24981860 details
MECP2C1orf35BioGRID24981860 details
MECP2MFAP1BioGRID24981860 details
MECP2TACO1BioGRID24981860 details
MECP2RPS19BioGRID24981860 details
MECP2ATXN2LBioGRID24981860 details
MECP2EPB41L2BioGRID24981860 details
MECP2LYARBioGRID24981860 details
MECP2CKAP4BioGRID24981860 details
MECP2NUSAP1BioGRID24981860 details
MECP2METTL17BioGRID24981860 details
MECP2TMA16BioGRID24981860 details
MECP2RBM25BioGRID24981860 details
MECP2PRPF38ABioGRID24981860 details
MECP2NUDT21BioGRID24981860 details
MECP2SART1BioGRID24981860 details
MECP2DCAF13BioGRID24981860 details
MECP2CSNK1DBioGRID24981860 details
MECP2TP53BioGRID32807901 details
MECP2APEX1BioGRID34079125 details
MECP2POLR1GBioGRID34079125 details
MECP2CENPABioGRID34079125 details
MECP2FBLBioGRID34079125 details
MECP2LMNABioGRID34079125 details
MECP2NUP50BioGRID34079125 details
MECP2RPS6BioGRID34079125 details
MECP2ZNF330BioGRID34079125 details
MECP2PPARGBioGRID21151932 details
MECP2ELAVL1BioGRID19322201 details