Entity Details

Primary name EXT1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ16394
EntryNameEXT1_HUMAN
FullNameExostosin-1
TaxID9606
Evidenceevidence at protein level
Length746
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesEXT1

GO terms

Show/Hide Table
GOName
GO:0000139 Golgi membrane
GO:0001501 skeletal system development
GO:0001503 ossification
GO:0001958 endochondral ossification
GO:0001974 blood vessel remodeling
GO:0002062 chondrocyte differentiation
GO:0002067 glandular epithelial cell differentiation
GO:0002524 hypersensitivity
GO:0003128 heart field specification
GO:0003416 endochondral bone growth
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0006024 glycosaminoglycan biosynthetic process
GO:0006486 protein glycosylation
GO:0007033 vacuole organization
GO:0007165 signal transduction
GO:0007369 gastrulation
GO:0007411 axon guidance
GO:0007492 endoderm development
GO:0007498 mesoderm development
GO:0008217 regulation of blood pressure
GO:0008375 acetylglucosaminyltransferase activity
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0009615 response to virus
GO:0009642 response to light intensity
GO:0010467 gene expression
GO:0014033 neural crest cell differentiation
GO:0015012 heparan sulfate proteoglycan biosynthetic process
GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
GO:0015020 glucuronosyltransferase activity
GO:0016021 integral component of membrane
GO:0016757 glycosyltransferase activity
GO:0017145 stem cell division
GO:0019882 antigen processing and presentation
GO:0021554 optic nerve development
GO:0021772 olfactory bulb development
GO:0030163 protein catabolic process
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0030199 collagen fibril organization
GO:0030204 chondroitin sulfate metabolic process
GO:0030210 heparin biosynthetic process
GO:0030509 BMP signaling pathway
GO:0032836 glomerular basement membrane development
GO:0033627 cell adhesion mediated by integrin
GO:0033692 cellular polysaccharide biosynthetic process
GO:0035176 social behavior
GO:0035249 synaptic transmission, glutamatergic
GO:0035988 chondrocyte proliferation
GO:0036022 limb joint morphogenesis
GO:0036336 dendritic cell migration
GO:0036339 lymphocyte adhesion to endothelial cell of high endothelial venule
GO:0042044 fluid transport
GO:0042060 wound healing
GO:0042311 vasodilation
GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity
GO:0042596 fear response
GO:0042803 protein homodimerization activity
GO:0043931 ossification involved in bone maturation
GO:0045165 cell fate commitment
GO:0045202 synapse
GO:0045453 bone resorption
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity
GO:0050891 multicellular organismal water homeostasis
GO:0050901 leukocyte tethering or rolling
GO:0051923 sulfation
GO:0055078 sodium ion homeostasis
GO:0060047 heart contraction
GO:0060070 canonical Wnt signaling pathway
GO:0060218 hematopoietic stem cell differentiation
GO:0060351 cartilage development involved in endochondral bone morphogenesis
GO:0060441 epithelial tube branching involved in lung morphogenesis
GO:0060506 smoothened signaling pathway involved in lung development
GO:0060560 developmental growth involved in morphogenesis
GO:0061484 hematopoietic stem cell homeostasis
GO:0061744 motor behavior
GO:0061974 perichondral bone morphogenesis
GO:0062094 stomach development
GO:0065003 protein-containing complex assembly
GO:0070593 dendrite self-avoidance
GO:0071503 response to heparin
GO:0071625 vocalization behavior
GO:0071711 basement membrane organization
GO:0071847 TNFSF11-mediated signaling pathway
GO:0072112 glomerular visceral epithelial cell differentiation
GO:0072498 embryonic skeletal joint development
GO:0097021 lymphocyte migration into lymphoid organs
GO:0097241 hematopoietic stem cell migration to bone marrow
GO:0120193 tight junction organization
GO:1901706 mesenchymal cell differentiation involved in bone development
GO:1904888 cranial skeletal system development
GO:1990823 response to leukemia inhibitory factor

Subcellular Location

Show/Hide Table
Subcellular Location
Endoplasmic reticulum membrane
Golgi apparatus membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR004263 Exostosin-likeFamilyFamily
IPR015338 Glycosyl transferase 64 domainDomainDomain
IPR027670 Exostosin-1FamilyFamily
IPR029044 Nucleotide-diphospho-sugar transferasesFamilyHomologous superfamily
IPR040911 Exostosin, GT47 domainDomainDomain

Diseases

Show/Hide Table