Entity Details

Primary name PLA2G5
Entity type gene
Source Source Link

Details

PrimaryID5322
RefseqGeneNG_032045
SymbolPLA2G5
Namephospholipase A2 group V
Chromosome1
Location1p36.13
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPA2G5_HUMAN

GO terms

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GOName
GO:0005509 calcium ion binding
GO:0005543 phospholipid binding
GO:0005576 extracellular region
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0006631 fatty acid metabolic process
GO:0006644 phospholipid metabolic process
GO:0006654 phosphatidic acid biosynthetic process
GO:0010518 positive regulation of phospholipase activity
GO:0010744 positive regulation of macrophage derived foam cell differentiation
GO:0019370 leukotriene biosynthetic process
GO:0032009 early phagosome
GO:0032010 phagolysosome
GO:0034374 low-density lipoprotein particle remodeling
GO:0034638 phosphatidylcholine catabolic process
GO:0035965 cardiolipin acyl-chain remodeling
GO:0036148 phosphatidylglycerol acyl-chain remodeling
GO:0036149 phosphatidylinositol acyl-chain remodeling
GO:0036150 phosphatidylserine acyl-chain remodeling
GO:0036151 phosphatidylcholine acyl-chain remodeling
GO:0036152 phosphatidylethanolamine acyl-chain remodeling
GO:0047498 calcium-dependent phospholipase A2 activity
GO:0047499 calcium-independent phospholipase A2 activity
GO:0050482 arachidonic acid secretion
GO:0050766 positive regulation of phagocytosis
GO:0055037 recycling endosome
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0090265 positive regulation of immune complex clearance by monocytes and macrophages
GO:0090385 phagosome-lysosome fusion
GO:0102567 phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
GO:0102568 phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
GO:1903028 positive regulation of opsonization
GO:1905036 positive regulation of antifungal innate immune response
GO:1905164 positive regulation of phagosome maturation

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PLA2G5PLA2G4AHPRD12124392 details