Entity Details

Primary name CXCL12
Entity type gene
Source Source Link

Details

PrimaryID6387
RefseqGeneNG_016861
SymbolCXCL12
NameC-X-C motif chemokine ligand 12
Chromosome10
Location10q11.21
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-04-24
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsSDF1_HUMAN

GO terms

Show/Hide Table
GOName
GO:0001666 response to hypoxia
GO:0001764 neuron migration
GO:0001938 positive regulation of endothelial cell proliferation
GO:0005102 signaling receptor binding
GO:0005178 integrin binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006874 cellular calcium ion homeostasis
GO:0006935 chemotaxis
GO:0006952 defense response
GO:0006955 immune response
GO:0007155 cell adhesion
GO:0007165 signal transduction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007411 axon guidance
GO:0008009 chemokine activity
GO:0008015 blood circulation
GO:0008064 regulation of actin polymerization or depolymerization
GO:0008083 growth factor activity
GO:0008344 adult locomotory behavior
GO:0009314 response to radiation
GO:0009408 response to heat
GO:0009615 response to virus
GO:0009897 external side of plasma membrane
GO:0010818 T cell chemotaxis
GO:0016032 viral process
GO:0022029 telencephalon cell migration
GO:0030335 positive regulation of cell migration
GO:0031100 animal organ regeneration
GO:0031640 killing of cells of other organism
GO:0033603 positive regulation of dopamine secretion
GO:0033622 integrin activation
GO:0038146 chemokine (C-X-C motif) ligand 12 signaling pathway
GO:0042379 chemokine receptor binding
GO:0043434 response to peptide hormone
GO:0045236 CXCR chemokine receptor binding
GO:0045666 positive regulation of neuron differentiation
GO:0045785 positive regulation of cell adhesion
GO:0048842 positive regulation of axon extension involved in axon guidance
GO:0050930 induction of positive chemotaxis
GO:0050965 detection of temperature stimulus involved in sensory perception of pain
GO:0050966 detection of mechanical stimulus involved in sensory perception of pain
GO:0060326 cell chemotaxis
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0070098 chemokine-mediated signaling pathway
GO:0090026 positive regulation of monocyte chemotaxis
GO:0090280 positive regulation of calcium ion import
GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1903237 negative regulation of leukocyte tethering or rolling
GO:1990478 response to ultrasound
GO:1990869 cellular response to chemokine
GO:2000406 positive regulation of T cell migration
GO:2000669 negative regulation of dendritic cell apoptotic process

Diseases

Show/Hide Table

Interactions

35 interactions

InteractorPartnerSourcesPublicationsLink
CXCL12DPP8MINT18275857 details
CXCL12DPP4HPRD, MINT11390394 18275857 21314817 details
CXCL12DAZAP2BioGRID, IntAct21988832 details
CXCL12CCL5bhf-ucl, BioGRID28381538 details
CXCL12PF4bhf-ucl, BioGRID10233851 28381538 details
CXCL12CCL13bhf-ucl, BioGRID28381538 details
CXCL12CCL11bhf-ucl, BioGRID28381538 details
CXCL12CCL21bhf-ucl, BioGRID28381538 details
CXCL12CXCL11bhf-ucl, BioGRID28381538 details
CXCL12CCL25bhf-ucl, BioGRID28381538 details
CXCL12CXCL17bhf-ucl, BioGRID28381538 details
CXCL12CXCL14bhf-ucl, BioGRID28381538 details
CXCL12CXCL12bhf-ucl, BioGRID, HPRD10954912 28381538 9618518 details
CXCL12CCL20bhf-ucl, BioGRID28381538 details
CXCL12CXCL10bhf-ucl, BioGRID28381538 details
CXCL12CXCL9bhf-ucl, BioGRID28381538 details
CXCL12CXCL6bhf-ucl, BioGRID28381538 details
CXCL12PF4V1bhf-ucl, BioGRID28381538 details
CXCL12CXCL2bhf-ucl, BioGRID28381538 details
CXCL12XCL2bhf-ucl, BioGRID28381538 details
CXCL12XCL1bhf-ucl, BioGRID28381538 details
CXCL12CCL28bhf-ucl, BioGRID28381538 details
CXCL12CCL26bhf-ucl, BioGRID28381538 details
CXCL12PPBPbhf-ucl, BioGRID28381538 details
CXCL12FN1BioGRID, HPRD11023498 details
CXCL12VCANBioGRID11083865 details
CXCL12FBXO7BioGRID27503909 details
CXCL12CXCR4BioGRID, HPRD10233851 21757744 25495026 8752281 details
CXCL12HMGB1BioGRID25495026 details
CXCL12ITGAVBioGRID23381805 details
CXCL12CD4HPRD10600606 details
CXCL12CTSGHPRD11241273 details
CXCL12MMP2HPRD11571304 details
CXCL12ELANEHPRD12068293 details
CXCL12PDIA6BioGRID, IntAct30021884 details