Entity Details

Primary name SLC6A2
Entity type gene
Source Source Link

Details

PrimaryID6530
RefseqGeneNG_016969
SymbolSLC6A2
Namesolute carrier family 6 member 2
Chromosome16
Location16q12.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1997-12-05
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsSC6A2_HUMAN

GO terms

Show/Hide Table
GOName
GO:0003779 actin binding
GO:0005326 neurotransmitter transmembrane transporter activity
GO:0005328 neurotransmitter:sodium symporter activity
GO:0005330 dopamine:sodium symporter activity
GO:0005334 norepinephrine:sodium symporter activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006836 neurotransmitter transport
GO:0007268 chemical synaptic transmission
GO:0008504 monoamine transmembrane transporter activity
GO:0009986 cell surface
GO:0015844 monoamine transport
GO:0015874 norepinephrine transport
GO:0016020 membrane
GO:0032809 neuronal cell body membrane
GO:0035725 sodium ion transmembrane transport
GO:0042493 response to drug
GO:0042734 presynaptic membrane
GO:0043005 neuron projection
GO:0043014 alpha-tubulin binding
GO:0045121 membrane raft
GO:0046872 metal ion binding
GO:0048265 response to pain
GO:0048487 beta-tubulin binding
GO:0051583 dopamine uptake involved in synaptic transmission
GO:0051620 norepinephrine uptake
GO:0070050 neuron cellular homeostasis

Diseases

Show/Hide Table
Disease IDSourceNameDescription
604715 OMIMOrthostatic intolerance (OI)Syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. It is associated with postural tachycardia. Plasma norepinephrine concentration is abnormally high. The disease is caused by variants affecting the gene represented in this entry.

Interactions

5 interactions